Gene Symbol | FBXW10 |
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Entrez Gene | 10517 |
Alt Symbol | Fbw10, HREP, SM25H2, SM2SH2 |
Species | Human |
Gene Type | protein-coding |
Description | F-box and WD repeat domain containing 10 |
Other Description | F-box and WD-40 domain protein 10|F-box/WD repeat-containing protein 10|ubiquitin ligase specificity factor |
Swissprots | Q9H0F0 C9JZD7 Q8TC00 C9JRY8 Q5XX13 |
Accessions | CBH19282 Q5XX13 AK310383 AL136822 CAB66756 AY729024 AAU43731 BC028364 AAH28364 BI828401 DB055860 XM_006721420 XP_006721483 XM_011523617 XP_011521919 XM_011523618 XP_011521920 XM_011523619 XP_011521921 XM_011523620 XP_011521922 XM_011523621 XP_011521923 XM_011523622 XP_011521924 XM_011523623 XP_011521925 XM_011523624 XP_011521926 XM_011523625 XP_011521927 XM_011523626 XP_011521928 XM_011523627 XP_011521929 XR_933968 NM_031456 NM_001267585 NP_001254514 NM_001267586 NP_001254515 NR_051988 |
Function | Probable substrate-recognition component of a SCF (SKP1- CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1. {ECO:0000269|PubMed:20498703}. |
FBXW10 CRISPR/Cas9 KO Plasmid (h) - sc-416742 from Santa Cruz Biotechnology
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FBXW10 HDR Plasmid (h) - sc-416742-HDR from Santa Cruz Biotechnology
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FBXW10 Double Nickase Plasmid (h) - sc-416742-NIC from Santa Cruz Biotechnology
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FBXW10 Double Nickase Plasmid (h2) - sc-416742-NIC-2 from Santa Cruz Biotechnology
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FBXW10 CRISPR Activation Plasmid (h) - sc-416742-ACT from Santa Cruz Biotechnology
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FBXW10 CRISPR Activation Plasmid (h2) - sc-416742-ACT-2 from Santa Cruz Biotechnology
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FBXW10 Lentiviral Activation Particles (h) - sc-416742-LAC from Santa Cruz Biotechnology
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FBXW10 Lentiviral Activation Particles (h2) - sc-416742-LAC-2 from Santa Cruz Biotechnology
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FBXW10 siRNA (h) - sc-93681 from Santa Cruz Biotechnology
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FBXW10 shRNA Plasmid (h) - sc-93681-SH from Santa Cruz Biotechnology
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FBXW10 shRNA (h) Lentiviral Particles - sc-93681-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU109601 from Sigma-Aldrich
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MISSION® esiRNA - EHU112991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8570 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8570 from Sigma-Aldrich
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FBXW10 siRNA (Human) - CRH7144 from Cohesion Biosciences
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FBXW10 - MBS8211716 from MyBioSource
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Human FBXW10 siRNA - orb267646 from Biorbyt
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FBXW10 shRNA Plasmid (Human) - CHH7144 from Cohesion Biosciences
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