Gene Symbol |
COA1
|
Entrez Gene |
55744
|
Alt Symbol |
C7orf44, MITRAC15
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
|
Other Description |
cytochrome c oxidase assembly factor 1 homolog|cytochrome c oxidase assembly protein 1 homolog|mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa
|
Swissprots |
Q9HAB7 A8KAH8 A6NJU8 Q9GZY4 Q9NVD2
|
Accessions |
EAW94165 EAW94166 EAW94167 EAW94168 EAW94169 EAW94170 Q9GZY4 AK001665 BAA91821 AK021905 BAB13932 AK023007 BAB14356 AK023053 BAB14379 AK097203 BAG53433 AK127933 AK129690 AK293043 BAF85732 AK308911 AK309315 BC056884 AAH56884 HQ448644 ADQ33122 XM_005249804 XP_005249861 XM_005249806 XP_005249863 XM_005249807 XP_005249864 XM_006715751 XP_006715814 XM_006715752 XP_006715815 XM_011515445 XP_011513747 XR_242093 XR_242094 XR_428082 XR_926939 XR_926940 XR_926941 NM_018224 NP_060694 NR_047701
|
Function |
Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for assembly of mitochondrial respiratory chain complex I and complex IV. {ECO:0000269|PubMed:23260140}.
|
Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:22356826, ECO:0000269|PubMed:23260140}; Single-pass membrane protein {ECO:0000269|PubMed:22356826, ECO:0000269|PubMed:23260140}.
|