Gene Symbol | COA1 |
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Entrez Gene | 55744 |
Alt Symbol | C7orf44, MITRAC15 |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
Other Description | cytochrome c oxidase assembly factor 1 homolog|cytochrome c oxidase assembly protein 1 homolog|mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa |
Swissprots | Q9HAB7 A8KAH8 A6NJU8 Q9GZY4 Q9NVD2 |
Accessions | EAW94165 EAW94166 EAW94167 EAW94168 EAW94169 EAW94170 Q9GZY4 AK001665 BAA91821 AK021905 BAB13932 AK023007 BAB14356 AK023053 BAB14379 AK097203 BAG53433 AK127933 AK129690 AK293043 BAF85732 AK308911 AK309315 BC056884 AAH56884 HQ448644 ADQ33122 XM_005249804 XP_005249861 XM_005249806 XP_005249863 XM_005249807 XP_005249864 XM_006715751 XP_006715814 XM_006715752 XP_006715815 XM_011515445 XP_011513747 XR_242093 XR_242094 XR_428082 XR_926939 XR_926940 XR_926941 NM_018224 NP_060694 NR_047701 |
Function | Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for assembly of mitochondrial respiratory chain complex I and complex IV. {ECO:0000269|PubMed:23260140}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:22356826, ECO:0000269|PubMed:23260140}; Single-pass membrane protein {ECO:0000269|PubMed:22356826, ECO:0000269|PubMed:23260140}. |
COA1 CRISPR/Cas9 KO Plasmid (h) - sc-416745 from Santa Cruz Biotechnology
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COA1 HDR Plasmid (h) - sc-416745-HDR from Santa Cruz Biotechnology
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COA1 Double Nickase Plasmid (h) - sc-416745-NIC from Santa Cruz Biotechnology
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COA1 Double Nickase Plasmid (h2) - sc-416745-NIC-2 from Santa Cruz Biotechnology
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COA1 CRISPR Activation Plasmid (h) - sc-416745-ACT from Santa Cruz Biotechnology
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COA1 CRISPR Activation Plasmid (h2) - sc-416745-ACT-2 from Santa Cruz Biotechnology
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COA1 Lentiviral Activation Particles (h) - sc-416745-LAC from Santa Cruz Biotechnology
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COA1 Lentiviral Activation Particles (h2) - sc-416745-LAC-2 from Santa Cruz Biotechnology
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COA1 siRNA (h) - sc-89447 from Santa Cruz Biotechnology
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COA1 shRNA Plasmid (h) - sc-89447-SH from Santa Cruz Biotechnology
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COA1 shRNA (h) Lentiviral Particles - sc-89447-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU082461 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5097 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5097 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02510 from Sigma-Aldrich
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COA1 siRNA (Human) - CRJ0882 from Cohesion Biosciences
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COA1 - MBS8238332 from MyBioSource
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shRNA set against Human C7orf44 (NM_018224.3) - SHH252457 from Creative biogene
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Human COA1 siRNA - orb271383 from Biorbyt
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COA1 shRNA Plasmid (Human) - CHJ0882 from Cohesion Biosciences
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COA1 miRNA 3'UTR clone - MiUTR3H-13392 from Creative biogene
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