UBE2A

Gene Symbol UBE2A
Entrez Gene 7319
Alt Symbol HHR6A, MRXS30, MRXSN, RAD6A, UBC2
Species Human
Gene Type protein-coding
Description ubiquitin-conjugating enzyme E2A
Other Description RAD6 homolog A|ubiquitin carrier protein A|ubiquitin-conjugating enzyme E2 A|ubiquitin-protein ligase A
Swissprots Q96FX4 A6NMF5 P49459 B2R7R9 D3DWI1 A6NGR2 Q4TTG1 A6NFE9
Accessions AAL58874 AAY46159 CBX53867 CBX53868 CBX53869 EAW89861 EAW89862 EAW89863 P49459 AI784380 AK223045 BAD96765 AK223064 BAD96784 AK297696 BAG60054 AK301675 BAG63148 AK313092 BAG35916 AL701289 BC010175 AAH10175 BC042021 BI093289 D28459 BAA05825 DA068506 DA599154 DQ893386 ABM84312 DQ896706 ABM87705 M74524 AAA35981 NM_001282161 NP_001269090 NM_003336 NP_003327 NM_181762 NP_861427 NM_181777
Function Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. {ECO:0000269|PubMed:16337599, ECO:0000269|PubMed:20061386}.
Top Pathways Ubiquitin mediated proteolysis

HR6A/HR6B Antibody - 4944 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa, ME-180, 293 and K562 cells, using HR6A/HR6B Antibody.

UBC2 (2782C5) - sc-81419 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
UBC2 (2782C5): sc-81419 Western Blot analysis of human recombinant UBC2 fusion protein.

UBE2A/B (G-9) - sc-365507 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
UBE2A/B (G-9): sc-365507. Western blot analysis of UBC2 expression in non-transfected: sc-117752 (A) and mouse UBC2 transfected: sc-124403 (B) 293T whole cell lysates.

UBE2A/B (A-18) - sc-10479 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

UBE2A/B (H-75) - sc-30078 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
UBE2A/B (H-75): sc-30078. Western blot analysis of UBE2A/B expression in non-transfected: sc-117752 (A) and mouse UBC2 transfected: sc-124403 (B) 293T whole cell lysates.

UBE2A/B (P-12) - sc-27526 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Rad6 antibody - ab155001 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Rad6 antibody (ab155001) at 1/500 dilution + Mouse brain (whole cell lysate) at 50 µg

Anti-Rad6 antibody [2782C5] - ab50889 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2782C5
Anti-Rad6 antibody [2782C5] (ab50889) + immunizing peptide

Anti-Rad6 antibody - BSA and Azide free - ab179848 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Rad6 antibody - BSA and Azide free (ab179848) at 1/1000 dilution + HeLa whole cell extract at 10 µg

Anti-UBE2A Antibody (aa10-50) - LS-C287188 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human Rad6 by Immunohistochemistry. Sample: FFPE section of human stomach carcinoma. Antibody: Affinity purified rabbit anti-Rad6 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

Anti-UBE2A Antibody (N-Terminus) - LS-C287187 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse Rad6 by Immunohistochemistry. Sample: FFPE section of human stomach carcinoma (left) and mouse squamous cell carcinoma (right). Antibody: Affinity purified rabbit anti-Rad6 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

Anti-UBE2A Antibody (N-Terminus) - LS-C68244 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UBE2A Antibody - LS-C76681 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-UBE2A Antibody (aa10-50) - LS-C93552 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UBE2A Antibody (N-Terminus) - LS-C93551 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UBE2A Antibody (aa100-150) - LS-C93553 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UBE2A Antibody (clone 2782C5) - LS-C184423 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2782C5

Anti-UBE2A Antibody (clone 3D7-E2) - LS-C198392 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D7-E2

Anti-UBE2A Antibody (aa100-150) - LS-C287190 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human Rad6 by Western Blot. Samples: Whole cell lysate (50 ug) from 293T cells. Antibody: Affinity purified rabbit anti-Rad6 antibody used at the indicated concentrations. Detection: Chemiluminescence.

Anti-UBE2A Antibody - LS-C332004 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using UBE2A antibody.

Anti-UBE2A Antibody (clone 2782C5) - LS-C342465 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2782C5
Western blot analysis of immunized recombinant protein, using anti-UBE2A monoclonal antibody.

Anti-UBE2A Antibody (N-Terminus) - LS-C286350 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse Rad6 by Immunohistochemistry. Sample: FFPE section of mouse squamous cell carcinoma. Antibody: Affinity purified rabbit anti-Rad6 used at a dilution of 1:250. Detection: DAB staining using anti-Rabbit IHC antibody at a dilution of 1:100.

HR6A/UBE2A Antibody - NB100-553 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: HR6A/UBE2A Antibody [NB100-553] - Sample: FFPE section of human stomach carcinoma (left) and mouse squamous cell carcinoma (right). Antibody: Affinity purified rabbit anti- Rad6 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB

HR6A/UBE2A Antibody - NBP2-20780 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UBE2A Antibody [NBP2-20780] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 15% SDS PAGE gel, diluted at 1:500.

HR6A/UBE2A Antibody - NB100-555 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HR6A/UBE2A Antibody [NB100-555] - Whole cell lysate (50 ug) from 293T cells.
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