UBE2A

Gene Symbol UBE2A
Entrez Gene 7319
Alt Symbol HHR6A, MRXS30, MRXSN, RAD6A, UBC2
Species Human
Gene Type protein-coding
Description ubiquitin-conjugating enzyme E2A
Other Description RAD6 homolog A|ubiquitin carrier protein A|ubiquitin-conjugating enzyme E2 A|ubiquitin-protein ligase A
Swissprots Q96FX4 A6NMF5 P49459 B2R7R9 D3DWI1 A6NGR2 Q4TTG1 A6NFE9
Accessions AAL58874 AAY46159 CBX53867 CBX53868 CBX53869 EAW89861 EAW89862 EAW89863 P49459 AI784380 AK223045 BAD96765 AK223064 BAD96784 AK297696 BAG60054 AK301675 BAG63148 AK313092 BAG35916 AL701289 BC010175 AAH10175 BC042021 BI093289 D28459 BAA05825 DA068506 DA599154 DQ893386 ABM84312 DQ896706 ABM87705 M74524 AAA35981 NM_001282161 NP_001269090 NM_003336 NP_003327 NM_181762 NP_861427 NM_181777
Function Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. {ECO:0000269|PubMed:16337599, ECO:0000269|PubMed:20061386}.
Top Pathways Ubiquitin mediated proteolysis

Human-UBE2A-cDNA-Clone - DC02884 from Abgent, a WuXi AppTec company

Prices $103.95
Sizes 10 µg
Species Human
Accession NM_003336

UBE2A - MBS1271730 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC010175

Human UBE2A cDNA clone(NM_181762.1) - CDFG011831 from Creative Biomart

Species Human
Accession NM_181762.1

Human UBE2A cDNA clone(NM_181777.1) - CDFG011839 from Creative Biomart

Species Human
Accession NM_181777.1

Human UBE2A cDNA clone(NM_003336.2) - CDFH020728 from Creative Biomart

Species Human
Accession NM_003336.2

Human UBE2A ORF Clone(NM_181762.1) - CDCL180261 from Creative Biomart

Species Human
Accession NM_181762.1

Human UBE2A ORF Clone(NM_003336.2) - CDCL180262 from Creative Biomart

Species Human
Accession NM_003336.2

Human UBE2A ORF Clone(NM_003336.2) - CDCR285428 from Creative Biomart

Species Human
Accession NM_003336.2

Human UBE2A ORF Clone(NM_003336.2) - CDCR285429 from Creative Biomart

Species Human
Accession NM_003336.2

Human UBE2A ORF Clone(NM_003336.2) - CDCR285430 from Creative Biomart

Species Human
Accession NM_003336.2

Human UBE2A ORF Clone(NM_181762.1) - CDCR324180 from Creative Biomart

Species Human
Accession NM_181762.1

Human UBE2A ORF Clone(NM_181762.1) - CDCR324181 from Creative Biomart

Species Human
Accession NM_181762.1

Human UBE2A ORF Clone(NM_181777.1) - CDCR324192 from Creative Biomart

Species Human
Accession NM_181777.1

Human UBE2A ORF Clone(NM_181777.1) - CDCR324193 from Creative Biomart

Species Human
Accession NM_181777.1

human UBE2A ORF clone - CDCH097318 from Creative Biomart

Species Human
Accession NM_003336

human UBE2A ORF clone - CDCH097319 from Creative Biomart

Species Human
Accession NM_003336

human UBE2A ORF clone - CDCH097320 from Creative Biomart

Species Human
Accession NM_003336

human UBE2A ORF clone - CDCH097321 from Creative Biomart

Species Human
Accession NM_003336

human UBE2A ORF clone - CDCH097322 from Creative Biomart

Species Human
Accession NM_003336

human UBE2A ORF clone - CDCH097323 from Creative Biomart

Species Human
Accession NM_003336

human UBE2A ORF clone - CDCH097324 from Creative Biomart

Species Human
Accession NM_003336

human UBE2A ORF clone - CDCH097325 from Creative Biomart

Species Human
Accession NM_003336

human UBE2A ORF clone (NM_181762.1) - CDCH097320 from Creative biogene

Species Human

human UBE2A ORF clone (NM_181777.1) - CDCH097322 from Creative biogene

Species Human

human UBE2A ORF clone (NM_003336.2) - CDCH097324 from Creative biogene

Species Human
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