Gene Symbol | CLCN4 |
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Entrez Gene | 1183 |
Alt Symbol | CLC4, ClC-4, ClC-4A |
Species | Human |
Gene Type | protein-coding |
Description | chloride channel, voltage-sensitive 4 |
Other Description | H(+)/Cl(-) exchange transporter 4|chloride channel 4|chloride channel protein 4|chloride transporter ClC-4 |
Swissprots | Q9UBU1 B7Z5Z4 A1L3U1 P51793 |
Accessions | AAC83175 EAW98777 EAW98778 P51793 AB019432 BAA77327 AF052117 AF170492 AAD50981 AK225287 AK289564 BAF82253 AK299611 BAH13080 BC036068 AAH36068 BC130278 AAI30279 BP310547 HQ258498 ADR83252 X77197 CAA54417 NM_001256944 NP_001243873 NM_001830 NP_001821 |
Function | Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. {ECO:0000269|PubMed:18063579}. |
Subcellular Location | Early endosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Late endosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Abundant in skeletal muscle and also detectable in brain and heart. |
CLC-4 CRISPR/Cas9 KO Plasmid (h) - sc-409169 from Santa Cruz Biotechnology
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CLC-4 HDR Plasmid (h) - sc-409169-HDR from Santa Cruz Biotechnology
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CLC-4 Double Nickase Plasmid (h) - sc-409169-NIC from Santa Cruz Biotechnology
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CLC-4 Double Nickase Plasmid (h2) - sc-409169-NIC-2 from Santa Cruz Biotechnology
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CLC-4 CRISPR Activation Plasmid (h) - sc-409169-ACT from Santa Cruz Biotechnology
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CLC-4 CRISPR Activation Plasmid (h2) - sc-409169-ACT-2 from Santa Cruz Biotechnology
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CLC-4 Lentiviral Activation Particles (h) - sc-409169-LAC from Santa Cruz Biotechnology
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CLC-4 Lentiviral Activation Particles (h2) - sc-409169-LAC-2 from Santa Cruz Biotechnology
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CLC-4 siRNA (h) - sc-42383 from Santa Cruz Biotechnology
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CLC-4 shRNA Plasmid (h) - sc-42383-SH from Santa Cruz Biotechnology
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CLC-4 shRNA (h) Lentiviral Particles - sc-42383-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU153601 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2024 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2024 from Sigma-Aldrich
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CLCN4 siRNA (Human) - CRH0845 from Cohesion Biosciences
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CLCN4 RNAi - H00001183-R01 from Novus Biologicals
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CLCN4 - MBS8227763 from MyBioSource
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shRNA set against Human CLCN4 (NM_001830.3) - SHH264573 from Creative biogene
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Human CLCN4 siRNA - orb261347 from Biorbyt
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CLCN4 shRNA Plasmid (Human) - CHH0845 from Cohesion Biosciences
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CLCN4 miRNA 3'UTR clone - MiUTR1H-02185 from Creative biogene
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