DIDO1
| Gene Symbol | DIDO1 |
|---|---|
| Entrez Gene | 11083 |
| Alt Symbol | BYE1, C20orf158, DATF-1, DATF1, DIDO2, DIDO3, DIO-1, DIO1, dJ885L7.8 |
| Species | Human |
| Gene Type | protein-coding |
| Description | death inducer-obliterator 1 |
| Other Description | death-associated transcription factor 1|death-inducer obliterator 1 |
| Swissprots | Q9UFB6 Q9BW03 Q9NUM8 A8MY65 E1P5I1 Q9H4G6 Q3ZTL8 Q9BQW0 Q4VXS2 Q9NTU8 Q9BTC0 Q96D72 O15043 Q4VXS1 Q9H4G7 B9EH82 Q4VXV9 Q4VXV8 Q3ZTL7 |
| Accessions | EAW75321 EAW75322 EAW75323 EAW75324 EAW75325 EAW75326 Q9BTC0 AB002331 BAA20791 AF085876 AI291497 AK002127 BAA92094 AK127121 AL133063 CAB61387 AW206895 AY481571 AAS49898 AY481572 AAS49899 BC000770 AAH00770 BC004237 AAH04237 BC012757 BC014489 AAH14489 BC014615 BC137177 AAI37178 BG677268 BG755041 BG771506 BI830580 BQ045451 BX404270 CD637702 CK300739 CN348577 CN348578 CN370110 CN370112 DA294135 DA506324 DB460917 DQ893020 ABM83946 DQ896265 ABM87264 LK937967 XM_011528504 XP_011526806 XM_011528505 XP_011526807 XM_011528506 XP_011526808 XM_011528507 XP_011526809 XM_011528508 XP_011526810 XM_011528509 XP_011526811 XM_011528510 XP_011526812 NM_001193369 NP_001180298 NM_001193370 NP_001180299 NM_022105 NP_071388 NM_033081 NP_149072 NM_080796 NP_542986 NM_080797 NP_542987 |
| Function | Putative transcription factor, weakly pro-apoptotic when overexpressed (By similarity). Tumor suppressor. Required for early embryonic stem cell development. {ECO:0000250, ECO:0000269|PubMed:16127461}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00651}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:23831028}. Note=Translocates to the nucleus after pro-apoptotic stimuli (By similarity). Translocates to the mitotic spindle upon loss of interaction with H3K4me3 during early mitosis. {ECO:0000250}. |
| Tissue Specificity | Ubiquitous. |
Dio-1 CRISPR/Cas9 KO Plasmid (h) - sc-416861 from Santa Cruz Biotechnology
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Dio-1 HDR Plasmid (h) - sc-416861-HDR from Santa Cruz Biotechnology
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Dio-1 Double Nickase Plasmid (h) - sc-416861-NIC from Santa Cruz Biotechnology
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Dio-1 Double Nickase Plasmid (h2) - sc-416861-NIC-2 from Santa Cruz Biotechnology
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Dio-1 CRISPR Activation Plasmid (h) - sc-416861-ACT from Santa Cruz Biotechnology
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Dio-1 CRISPR Activation Plasmid (h2) - sc-416861-ACT-2 from Santa Cruz Biotechnology
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Dio-1 Lentiviral Activation Particles (h) - sc-416861-LAC from Santa Cruz Biotechnology
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Dio-1 Lentiviral Activation Particles (h2) - sc-416861-LAC-2 from Santa Cruz Biotechnology
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Dio-1 siRNA (h) - sc-35194 from Santa Cruz Biotechnology
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Dio-1 shRNA Plasmid (h) - sc-35194-SH from Santa Cruz Biotechnology
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Dio-1 shRNA (h) Lentiviral Particles - sc-35194-V from Santa Cruz Biotechnology
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DIDO1 RNAi - H00011083-R02 from Novus Biologicals
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DIDO1 RNAi - H00011083-R03 from Novus Biologicals
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DIDO1 RNAi - H00011083-R04 from Novus Biologicals
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MISSION® esiRNA - EHU079271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7234 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7234 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07372 from Sigma-Aldrich
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DIDO1 siRNA (Human) - CRH7580 from Cohesion Biosciences
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DIDO1 RNAi - H00011083-R01 from Novus Biologicals
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DIDO1 - MBS8226997 from MyBioSource
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shRNA set against Human DIDO1 (NM_022105.4) - SHH278065 from Creative biogene
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DIDO1 shRNA Plasmid (Human) - CHH7580 from Cohesion Biosciences
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DIDO1 miRNA 3'UTR clone - MiUTR3H-06587 from Creative biogene
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DIDO1 miRNA 3'UTR clone - MiUTR3H-06588 from Creative biogene
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