Cd40lg

Gene Symbol Cd40lg
Entrez Gene 21947
Alt Symbol CD154, CD40-L, Cd40l, HIGM1, IGM, IMD3, Ly-62, Ly62, T-BAM, TRAP, Tnfsf5, gp39
Species Mouse
Gene Type protein-coding
Description CD40 ligand
Other Description T-cell antigen Gp39|TNF-related activation protein|tumor necrosis factor ligand superfamily member 5
Swissprots P27548
Accessions AAC13639 AAC13640 CAL44886 CBY45345 EDL42166 P27548 BC119225 AAI19226 EU274582 ABX76043 X65453 CAA46448 NM_011616 NP_035746
Function Cytokine that binds to TNFRSF5. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane; Single-pass type II membrane protein.
Tissue Specificity Specifically expressed on activated CD4+ T- lymphocytes.
Top Pathways Cytokine-cytokine receptor interaction, Primary immunodeficiency, Allograft rejection, Autoimmune thyroid disease, Intestinal immune network for IgA production

Anti-CD40L antibody [AP-MAB0820] - ab83050 from Abcam

Prices $370.00
Sizes 500 µg
Clonality Monoclonal
Clone AP-MAB0820

Anti-CD40L antibody [MR-1] - ab99895 from Abcam

Prices $378.00
Sizes 100 µg
Clonality Monoclonal
Clone MR-1

Anti-CD40L antibody [MR-1] - ab99894 from Abcam

Prices $372.00
Sizes 100 µg
Clonality Monoclonal
Clone MR-1

Anti-CD40L antibody [MR1] - ab25206 from Abcam

Prices $372.00
Sizes 250 µg
Clonality Monoclonal
Clone MR1

Anti-CD40L antibody [MR1] (Allophycocyanin) - ab93570 from Abcam

Prices $376.00
Sizes 50 µg
Clonality Monoclonal
Clone MR1
Staining of 6 hour PMA and Ionomycin treated isolated T cells from Mouse splenocytes with 0.125 µg of APC Armenian Hamster IgG Isotype Control (open histogram) or 0.125 µg of ab93570 (colored histogram). Total viable cells were used for analysis.

Anti-CD40L antibody [MR1] (Biotin) - ab24966 from Abcam

Prices $370.00
Sizes 250 µg
Clonality Monoclonal
Clone MR1

Anti-CD40L antibody [MR1] (FITC) - ab24934 from Abcam

Prices $188.00
Sizes 50 µg
Clonality Monoclonal
Clone MR1
Partially purified spleen T cells from BALB/c mice were incubated with either hamster IgG or plate bound hamster anti mouse CD3 epsilon for 7 hours at 37°C. The cells were then harvested, double stained with ab24934 (2µg for 106 cells) and anti CD4+8 PE, and analyzed by flow cytometry.

Anti-CD40L antibody [MR1] (Phycoerythrin) - ab25568 from Abcam

Prices $370.00
Sizes 50 µg
Clonality Monoclonal
Clone MR1

CD40 Ligand/TNFSF5 Antibody [Unconjugated] - AF1163 from Novus Biologicals

Prices $99.00, $369.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Recombinant Mouse CD40 Ligand/TNFSF5 (Catalog # 8230-CL) induces proliferation in mouse splenic B cells in a dose-dependent manner (orange line), as measured by Resazurin (Catalog # AR002). Proliferation elicited by Recombinant Mouse CD40 Ligand/TNFSF5 (0.5 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse CD40 Ligand/TNFSF5 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1163). The ND50 is typically 0.08-0.4 µg/mL.

CD40 Ligand/TNFSF5 Antibody (MR-1) - NBP1-47234 from Novus Biologicals

Prices $199.00
Sizes 100 µg
Host Hamster
Clonality Monoclonal
Clone MR-1

CD40 Ligand/TNFSF5 Antibody (AP-MAB0712) - NBP2-12167 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Hamster
Clonality Monoclonal
Clone AP-MAB0712

Mouse IgM Antibody (LO-MM-9) - NBP1-42328 from Novus Biologicals

Prices $229.00
Sizes 200 µl
Host Rat
Clonality Monoclonal
Clone LO-MM-9

Mouse IgM Antibody - NBP1-45167 from Novus Biologicals

Prices $279.00
Sizes 500 µg
Host Goat
Clonality Polyclonal

CD40 Ligand/TNFSF5 Antibody (208109) [Allophycocyanin] - FAB1163A from Novus Biologicals

Prices $289.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 208109

Mouse IgM Antibody (MM-30) [Allophycocyanin] - NBP2-27284APC from Novus Biologicals

Prices $169.00
Sizes 25 tests
Host Mouse
Clonality Monoclonal
Clone MM-30

CD40 Ligand/TNFSF5 Antibody [Biotin] - BAF1163 from Novus Biologicals

Prices $420.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
CD40 Ligand/TNFSF5 was detected in immersion fixed mouse splenocytes either stimulated with PHA (left panel) or untreated (right panel) using Goat Anti-Mouse CD40 Ligand/TNFSF5 Biotinylated Antigen Affinity-purified Polyclonal Antibody (Catalog # BAF1163) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Streptavidin (red; Catalog # NL999) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Non-adherent Cells.

Mouse IgM Antibody (MM-30) [Alexa Fluor (R) 700] - NBP2-27284AF700 from Novus Biologicals

Prices $159.00
Sizes 25 tests
Host Mouse
Clonality Monoclonal
Clone MM-30

Mouse IgM Antibody (MM-30) [Alexa Fluor (R) 647] - NBP2-27284AF647 from Novus Biologicals

Prices $159.00
Sizes 25 tests
Host Mouse
Clonality Monoclonal
Clone MM-30

Mouse IgM Antibody (MM-30) [Alexa Fluor (R) 488] - NBP2-27284AF488 from Novus Biologicals

Prices $169.00
Sizes 25 tests
Host Mouse
Clonality Monoclonal
Clone MM-30

Mouse IgM Antibody (MM-30) [Alexa Fluor (R) 405] - NBP2-27284AF405 from Novus Biologicals

Prices $159.00
Sizes 25 tests
Host Mouse
Clonality Monoclonal
Clone MM-30

Mouse IgM Antibody (MM-30) [7C] - NBP2-27284V2 from Novus Biologicals

Prices $159.00
Sizes 25 tests
Host Mouse
Clonality Monoclonal
Clone MM-30

Mouse IgM Antibody (MM-30) [DyLight 405] - NBP2-27284V from Novus Biologicals

Prices $159.00
Sizes 25 tests
Host Mouse
Clonality Monoclonal
Clone MM-30

Mouse IgM Antibody (MM-30) [DyLight 350] - NBP2-27284UV from Novus Biologicals

Prices $159.00
Sizes 25 tests
Host Mouse
Clonality Monoclonal
Clone MM-30

Mouse IgM Antibody (MM-30) [DyLight 550] - NBP2-27284R from Novus Biologicals

Prices $159.00
Sizes 25 tests
Host Mouse
Clonality Monoclonal
Clone MM-30

Mouse IgM Antibody (MM-30) [PE] - NBP2-27284PE from Novus Biologicals

Prices $159.00
Sizes 25 tests
Host Mouse
Clonality Monoclonal
Clone MM-30
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