CAMKK1

Gene Symbol CAMKK1
Entrez Gene 84254
Alt Symbol CAMKKA
Species Human
Gene Type protein-coding
Description calcium/calmodulin-dependent protein kinase kinase 1, alpha
Other Description CAMKK alpha protein|caM-KK 1|caM-KK alpha|caM-kinase IV kinase|caM-kinase kinase 1|caM-kinase kinase alpha|caMKK 1|calcium/calmodulin-dependent protein kinase kinase 1|calcium/calmodulin-dependent protein kinase kinase alpha
Swissprots Q9BQH3 Q8N5S9
Accessions EAW90474 EAW90475 EAW90476 Q8N5S9 AF370377 AAQ15213 AF425232 AAN37386 AF425301 AAN37387 AK128601 AL136576 CAB66511 BC011401 BC031647 AAH31647 BC043487 AAH43487 DQ892421 ABM83347 DQ895635 ABM86561 XM_005256817 XP_005256874 XM_006721588 XP_006721651 XM_011524030 XP_011522332 XM_011524031 XP_011522333 XM_011524032 XP_011522334 XM_011524033 XP_011522335 XM_011524034 XP_011522336 XM_011524035 XP_011522337 XR_934115 NM_032294 NP_115670 NM_172206 NP_757343 NM_172207 NP_757344
Function Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death. {ECO:0000269|PubMed:12935886}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Top Pathways Adipocytokine signaling pathway, Alcoholism, Oxytocin signaling pathway, AMPK signaling pathway

CaMKKα (N-20) - sc-1548 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CaMKKα (R-73) - sc-11370 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CaMKKα (R-73): sc-11370. Immunoperoxidase staining of formalin fixed, paraffin-embedded human adrenal gland tissue showing cytoplasmic staining of cortical cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

CaMKKα (6) - sc-136280 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
CaMKKα (6): sc-136280. Western blot analysis of CaMKKα expression in rat brain tissue extract.

Anti-CaMKK antibody - ab80066 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab80066 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab80066, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-CaMKK antibody - ab57913 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
CaMKK antibody (ab57913) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human stomach.

Anti-CaMKK antibody - ab40123 from Abcam

Prices $370.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
ab40123 at a 1:50 dilution staining CaMKK in human brain tissue.

Anti-CaMKK antibody - ab56825 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CaMKK antibody [1F6] - ab117594 from Abcam

Prices $464.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1F6
ab117594, at 5µg/ml, staining CaMKK in Formalin-Fixed and Paraffin-Embedded Human adrenal tissue by immunohistochemistry.

Anti-CaMKK antibody [EPR10018] - ab174289 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10018
All lanes : Anti-CaMKK antibody [EPR10018] (ab174289) at 1/1000 dilutionLane 1 : Human fetal brain tissue lyateLane 2 : HeLa cell lysateLane 3 : Jurkat cell lysateLane 4 : 293T cell lysateLysates/proteins at 10 µg per lane.

Anti-CaMKK antibody, prediluted - ab53902 from Abcam

Prices $370.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
Human brain stained with neat ab53902

Anti-CaMKK antibody - N-terminal - ab76534 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CaMKK antibody - N-terminal (ab76534) at 1/50 dilution + mouse cerebellum tissue lysates at 35 µg

Anti-CAMKK1 Antibody (aa1-132) - LS-C77620 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-CAMKK1 Antibody (aa487-505) - LS-C50418 from LifeSpan Bioscience

Prices $530.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal
Human brain stained with Anti-CaM kinase kinase alpha

Anti-CAMKK1 Antibody - LS-C309706 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CAMKK1 Antibody - LS-C306716 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-CAMKK1 Antibody (C-Terminus) - LS-C145453 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CAMKK1 / CaMKK antibody LS-C145453 Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.

Anti-CAMKK1 Antibody (aa150-200) - LS-C289390 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human CaMKK alpha by Immunohistochemistry. Sample: FFPE section of human lung carcinoma (left) and human prostate carcinoma (right). Antibody: Affinity purified rabbit anti-CaMKK alpha used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

Anti-CAMKK1 Antibody (aa455-505) - LS-C289391 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human CaMKK alpha by Immunohistochemistry. Sample: FFPE section of human lung carcinoma (left) and human prostate carcinoma (right). Antibody: Affinity purified rabbit anti-CaMKK alpha used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Anti-CAMKK1 Antibody (aa86-121) - LS-C96697 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of CAMKK1 (arrow) using rabbit polyclonal CAMKK1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CAMKK1 gene (Lane 2).

Anti-CAMKK1 Antibody (aa337-369) - LS-C96698 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of CAMKK1 (arrow) using rabbit polyclonal CAMKK1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CAMKK1 gene (Lane 2).

Anti-CAMKK1 Antibody (clone 1F6) IHC-plus™ - LS-B5477 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1F6
Anti-CAMKK1 / CaMKK antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5477 concentration 5 ug/ml.

Anti-CAMKK1 Antibody (aa10-31) - LS-C312676 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
CAMKK1 / CaMKK antibody. IHC(P): Rat Brain Tissue.

CaMKK alpha Antibody [Unconjugated] - AF4536 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line, CCD-1070Sk human foreskin fibroblast cell line, K562 human chronic myelogenous leukemia cell line, and human brain tissue. PVDF membrane was probed with 1 µg/mL of Human/Rat CaMKK alpha Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4536) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for CaMKK alpha at approximately 68 kDa (as indicated). This experiment was conducted using Immunoblot Buffer Group 1.

CaMKK alpha Antibody (1F6) - H00084254-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F6

CaMKK alpha Antibody - NBP1-42683 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CaMKK alpha Antibody [NBP1-42683] - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells. Antibodies: Affinity purified rabbit anti-CaMKK alpha antibody used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. CaMKK alpha was also immunoprecipitated by rabbit anti-CaMKK alpha antibody NBP1-42682, which recognizes an upstream epitope.
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