Gene Symbol | CAMKK1 |
---|---|
Entrez Gene | 84254 |
Alt Symbol | CAMKKA |
Species | Human |
Gene Type | protein-coding |
Description | calcium/calmodulin-dependent protein kinase kinase 1, alpha |
Other Description | CAMKK alpha protein|caM-KK 1|caM-KK alpha|caM-kinase IV kinase|caM-kinase kinase 1|caM-kinase kinase alpha|caMKK 1|calcium/calmodulin-dependent protein kinase kinase 1|calcium/calmodulin-dependent protein kinase kinase alpha |
Swissprots | Q9BQH3 Q8N5S9 |
Accessions | EAW90474 EAW90475 EAW90476 Q8N5S9 AF370377 AAQ15213 AF425232 AAN37386 AF425301 AAN37387 AK128601 AL136576 CAB66511 BC011401 BC031647 AAH31647 BC043487 AAH43487 DQ892421 ABM83347 DQ895635 ABM86561 XM_005256817 XP_005256874 XM_006721588 XP_006721651 XM_011524030 XP_011522332 XM_011524031 XP_011522333 XM_011524032 XP_011522334 XM_011524033 XP_011522335 XM_011524034 XP_011522336 XM_011524035 XP_011522337 XR_934115 NM_032294 NP_115670 NM_172206 NP_757343 NM_172207 NP_757344 |
Function | Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death. {ECO:0000269|PubMed:12935886}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Top Pathways | Adipocytokine signaling pathway, Alcoholism, Oxytocin signaling pathway, AMPK signaling pathway |