| Gene Symbol |
THG1L
|
| Entrez Gene |
54974
|
| Alt Symbol |
ICF45, IHG-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
|
| Other Description |
induced by high glucose-1|interphase cytoplasmic foci protein 45|probable tRNA(His) guanylyltransferase
|
| Swissprots |
Q53G12 Q7L5R3 Q9NWX6 D3DQJ5 Q9H0S2
|
| Accessions |
EAW61590 EAW61591 Q9NWX6 AF086486 AK000553 BAA91249 AK021663 BAB13870 AK023355 BAB14540 AK223119 BAD96839 AK304590 BAG65378 AL136669 CAB66604 AY463216 AAS21134 BC001523 AAH01523 BC001852 AAH01852 BC023521 AAH23521 CR533503 CAG38534 XM_005265939 XP_005265996 XM_011534591 XP_011532893 XM_011534592 XP_011532894 NM_017872 NP_060342
|
| Function |
Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis. {ECO:0000269|PubMed:21059936}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:15459185}. Note=Found near the nuclear membrane.
|
| Tissue Specificity |
Expressed in many tissues. {ECO:0000269|PubMed:15459185}.
|
![Western Blot: THG1L Overexpression Lysate (Adult Normal) [NBL1-16885] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for THG1L.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1674_THG1L%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16885-img0002.jpg)