| Gene Symbol |
NUDT14
|
| Entrez Gene |
256281
|
| Alt Symbol |
UGPP, UGPPase
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nudix (nucleoside diphosphate linked moiety X)-type motif 14
|
| Other Description |
UDP-sugar diphosphatase|UDPG pyrophosphatase|uridine diphosphate glucose pyrophosphatase
|
| Swissprots |
Q86SJ8 O95848
|
| Accessions |
AAD15563 EAW81902 EAW81903 EAW81904 EAW81905 O95848 AB087802 BAC65455 AK128196 BAG54649 AK310449 BC041584 AAH41584 BE671270 DA249638 DA409636 DB096906 HQ257983 ADR82737 XM_005267500 XP_005267557 NM_177533 NP_803877
|
| Function |
Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP- mannose.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:12429023}.
|
