Gene Symbol | NUDT14 |
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Entrez Gene | 256281 |
Alt Symbol | UGPP, UGPPase |
Species | Human |
Gene Type | protein-coding |
Description | nudix (nucleoside diphosphate linked moiety X)-type motif 14 |
Other Description | UDP-sugar diphosphatase|UDPG pyrophosphatase|uridine diphosphate glucose pyrophosphatase |
Swissprots | Q86SJ8 O95848 |
Accessions | AAD15563 EAW81902 EAW81903 EAW81904 EAW81905 O95848 AB087802 BAC65455 AK128196 BAG54649 AK310449 BC041584 AAH41584 BE671270 DA249638 DA409636 DB096906 HQ257983 ADR82737 XM_005267500 XP_005267557 NM_177533 NP_803877 |
Function | Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP- mannose. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12429023}. |
NUDT14 CRISPR/Cas9 KO Plasmid (h) - sc-415231 from Santa Cruz Biotechnology
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NUDT14 HDR Plasmid (h) - sc-415231-HDR from Santa Cruz Biotechnology
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NUDT14 Double Nickase Plasmid (h) - sc-415231-NIC from Santa Cruz Biotechnology
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NUDT14 Double Nickase Plasmid (h2) - sc-415231-NIC-2 from Santa Cruz Biotechnology
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NUDT14 CRISPR Activation Plasmid (h) - sc-415231-ACT from Santa Cruz Biotechnology
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NUDT14 CRISPR Activation Plasmid (h2) - sc-415231-ACT-2 from Santa Cruz Biotechnology
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NUDT14 Lentiviral Activation Particles (h) - sc-415231-LAC from Santa Cruz Biotechnology
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NUDT14 Lentiviral Activation Particles (h2) - sc-415231-LAC-2 from Santa Cruz Biotechnology
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NUDT14 siRNA (h) - sc-92194 from Santa Cruz Biotechnology
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NUDT14 shRNA Plasmid (h) - sc-92194-SH from Santa Cruz Biotechnology
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NUDT14 shRNA (h) Lentiviral Particles - sc-92194-V from Santa Cruz Biotechnology
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NUDT14 RNAi - H00256281-R02 from Novus Biologicals
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MISSION® esiRNA - EHU012061 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15592 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15592 from Sigma-Aldrich
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NUDT14 siRNA (Human) - CRJ6749 from Cohesion Biosciences
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shRNA set against Human NUDT14 (NM_177533.4) - SHH356060 from Creative biogene
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Human NUDT14 siRNA - orb277250 from Biorbyt
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NUDT14 shRNA Plasmid (Human) - CHJ6749 from Cohesion Biosciences
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NUDT14 miRNA 3'UTR clone - MiUTR3H-10489 from Creative biogene
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