| Gene Symbol |
HEBP2
|
| Entrez Gene |
23593
|
| Alt Symbol |
C6ORF34B, C6orf34, PP23, SOUL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
heme binding protein 2
|
| Other Description |
heme-binding protein 2|placental protein 23
|
| Swissprots |
Q9Y5Z4 Q96P57
|
| Accessions |
EAW47917 Q9Y5Z4 AF117616 AAD32099 AF411610 AAL07394 AK057928 AY427823 AAR88624 BC008205 AAH08205 BC010290 AAH10290 BC016806 AAH16806 BC016807 AAH16807 BC093037 AAH93037 BF974311 XR_942368 NM_014320 NP_055135
|
| Function |
Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions. Does not bind hemin. {ECO:0000269|PubMed:17098234}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:17098234}. Mitochondrion {ECO:0000269|PubMed:17098234}. Note=Mainly localized to the cytoplasm with a much lower abundance in the mitochondrion.
|
| Tissue Specificity |
Detected in placenta. {ECO:0000269|PubMed:2018407}.
|
