Gene Symbol | HEBP2 |
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Entrez Gene | 23593 |
Alt Symbol | C6ORF34B, C6orf34, PP23, SOUL |
Species | Human |
Gene Type | protein-coding |
Description | heme binding protein 2 |
Other Description | heme-binding protein 2|placental protein 23 |
Swissprots | Q9Y5Z4 Q96P57 |
Accessions | EAW47917 Q9Y5Z4 AF117616 AAD32099 AF411610 AAL07394 AK057928 AY427823 AAR88624 BC008205 AAH08205 BC010290 AAH10290 BC016806 AAH16806 BC016807 AAH16807 BC093037 AAH93037 BF974311 XR_942368 NM_014320 NP_055135 |
Function | Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions. Does not bind hemin. {ECO:0000269|PubMed:17098234}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17098234}. Mitochondrion {ECO:0000269|PubMed:17098234}. Note=Mainly localized to the cytoplasm with a much lower abundance in the mitochondrion. |
Tissue Specificity | Detected in placenta. {ECO:0000269|PubMed:2018407}. |
HEBP2 CRISPR/Cas9 KO Plasmid (h) - sc-410496 from Santa Cruz Biotechnology
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HEBP2 HDR Plasmid (h) - sc-410496-HDR from Santa Cruz Biotechnology
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HEBP2 Double Nickase Plasmid (h) - sc-410496-NIC from Santa Cruz Biotechnology
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HEBP2 Double Nickase Plasmid (h2) - sc-410496-NIC-2 from Santa Cruz Biotechnology
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HEBP2 CRISPR Activation Plasmid (h) - sc-410496-ACT from Santa Cruz Biotechnology
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HEBP2 CRISPR Activation Plasmid (h2) - sc-410496-ACT-2 from Santa Cruz Biotechnology
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HEBP2 Lentiviral Activation Particles (h) - sc-410496-LAC from Santa Cruz Biotechnology
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HEBP2 Lentiviral Activation Particles (h2) - sc-410496-LAC-2 from Santa Cruz Biotechnology
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HEBP2 siRNA (h) - sc-95252 from Santa Cruz Biotechnology
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HEBP2 shRNA Plasmid (h) - sc-95252-SH from Santa Cruz Biotechnology
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HEBP2 shRNA (h) Lentiviral Particles - sc-95252-V from Santa Cruz Biotechnology
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HEBP2 RNAi - H00023593-R01 from Novus Biologicals
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MISSION® esiRNA - EHU016991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9957 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9957 from Sigma-Aldrich
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HEBP2 siRNA (Human) - CRH8383 from Cohesion Biosciences
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HEBP2 - MBS8225816 from MyBioSource
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shRNA set against Human HEBP2 (NM_014320.2) - SHH311341 from Creative biogene
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shRNA set against Human HEBP2(NM_014320.2) - SHH117677 from Creative biogene
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HEBP2 shRNA Plasmid (Human) - CHH8383 from Cohesion Biosciences
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HEBP2 miRNA 3'UTR clone - MiUTR1H-04446 from Creative biogene
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