| Gene Symbol |
Nqo1
|
| Entrez Gene |
18104
|
| Alt Symbol |
AV001255, Dia4, Dtd, Nmo-1, Nmo1, Nmor1, Ox-1, Ox1, Qr1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
NAD(P)H dehydrogenase, quinone 1
|
| Other Description |
DT-diaphorase|NAD(P)H dehydrogenase (quinone)|NAD(P)H dehydrogenase [quinone] 1|NAD(P)H menadione oxidoreductase 1, dioxin inducible|NAD(P)H:quinone oxidoreductase 1|azoreductase|diaphorase 4 (NADH/NADPH)|menadione reductase|phylloquinone reductase|quinone reductase 1
|
| Swissprots |
Q64669
|
| Accessions |
EDL11407 Q64669 AA982077 AK075568 BAC35826 AK157369 BC004579 AAH04579 CT010284 CAJ18492 S75951 AAB32718 U12961 AAA80184 NM_008706 NP_032732
|
| Function |
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm.
|
| Top Pathways |
Ubiquinone and other terpenoid-quinone biosynthesis
|