Gene Symbol | Nqo1 |
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Entrez Gene | 18104 |
Alt Symbol | AV001255, Dia4, Dtd, Nmo-1, Nmo1, Nmor1, Ox-1, Ox1, Qr1 |
Species | Mouse |
Gene Type | protein-coding |
Description | NAD(P)H dehydrogenase, quinone 1 |
Other Description | DT-diaphorase|NAD(P)H dehydrogenase (quinone)|NAD(P)H dehydrogenase [quinone] 1|NAD(P)H menadione oxidoreductase 1, dioxin inducible|NAD(P)H:quinone oxidoreductase 1|azoreductase|diaphorase 4 (NADH/NADPH)|menadione reductase|phylloquinone reductase|quinone reductase 1 |
Swissprots | Q64669 |
Accessions | EDL11407 Q64669 AA982077 AK075568 BAC35826 AK157369 BC004579 AAH04579 CT010284 CAJ18492 S75951 AAB32718 U12961 AAA80184 NM_008706 NP_032732 |
Function | The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. {ECO:0000250}. |
Subcellular Location | Cytoplasm. |
Top Pathways | Ubiquinone and other terpenoid-quinone biosynthesis |
NQO1 CRISPR/Cas9 KO Plasmid (m) - sc-421913 from Santa Cruz Biotechnology
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NQO1 HDR Plasmid (m) - sc-421913-HDR from Santa Cruz Biotechnology
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NQO1 Double Nickase Plasmid (m) - sc-421913-NIC from Santa Cruz Biotechnology
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NQO1 Double Nickase Plasmid (m2) - sc-421913-NIC-2 from Santa Cruz Biotechnology
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NQO1 CRISPR Activation Plasmid (m) - sc-421913-ACT from Santa Cruz Biotechnology
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NQO1 CRISPR Activation Plasmid (m2) - sc-421913-ACT-2 from Santa Cruz Biotechnology
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NQO1 Lentiviral Activation Particles (m) - sc-421913-LAC from Santa Cruz Biotechnology
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NQO1 Lentiviral Activation Particles (m2) - sc-421913-LAC-2 from Santa Cruz Biotechnology
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NQO1 siRNA (m) - sc-37140 from Santa Cruz Biotechnology
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NQO1 shRNA Plasmid (m) - sc-37140-SH from Santa Cruz Biotechnology
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NQO1 shRNA (m) Lentiviral Particles - sc-37140-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU088081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN36643 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND36643 from Sigma-Aldrich
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NQO1 siRNA (Mouse) - CRM2791 from Cohesion Biosciences
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shRNA set against Mouse NQO1 (NM_008706.5) - SHH354592 from Creative biogene
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shRNA set against Mouse Nqo1(NM_008706.5) - SHR019614 from Creative biogene
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NQO1 shRNA Plasmid (Mouse) - CHM2791 from Cohesion Biosciences
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NQO1 miRNA 3'UTR clone - MiUTR1M-07796 from Creative biogene
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