| Gene Symbol |
LMBRD1
|
| Entrez Gene |
55788
|
| Alt Symbol |
C6orf209, LMBD1, MAHCF, NESI
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
LMBR1 domain containing 1
|
| Other Description |
HDAg-L-interacting protein NESI|hepatitis delta antigen-L interacting protein|liver regeneration p-53 related protein|nuclear export signal-interacting protein|probable lysosomal cobalamin transporter
|
| Swissprots |
Q5VUN6 Q96FW4 Q9NUN5 Q9NZD6 E1P531 A8K204 Q86Y70 Q9BY56
|
| Accessions |
EAW48831 EAW48832 EAW48833 EAW48834 EAW48835 Q9NUN5 AB074281 AF113224 AAG39295 AF208863 AAF64277 AF211480 AAK26247 AK002102 BAA92087 AK021916 AK225187 AK225537 AK290069 BAF82758 AY136817 AAN11301 BC010360 AAH10360 BC047073 AAH47073 BJ995961 BX647737 DA028310 XM_006715511 XP_006715574 XM_011535941 XP_011534243 NM_018368 NP_060838
|
| Function |
Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. Isoform 3 may play a role in the assembly of hepatitis delta virus (HDV). {ECO:0000269|PubMed:15956556, ECO:0000269|PubMed:19136951}.
|
| Subcellular Location |
Lysosome membrane {ECO:0000269|PubMed:19136951}; Multi-pass membrane protein {ECO:0000269|PubMed:19136951}.
|
| Tissue Specificity |
Isoform 3 is expressed in liver. {ECO:0000269|PubMed:15956556}.
|
| Top Pathways |
Vitamin digestion and absorption
|