Gene Symbol | LMBRD1 |
---|---|
Entrez Gene | 55788 |
Alt Symbol | C6orf209, LMBD1, MAHCF, NESI |
Species | Human |
Gene Type | protein-coding |
Description | LMBR1 domain containing 1 |
Other Description | HDAg-L-interacting protein NESI|hepatitis delta antigen-L interacting protein|liver regeneration p-53 related protein|nuclear export signal-interacting protein|probable lysosomal cobalamin transporter |
Swissprots | Q5VUN6 Q96FW4 Q9NUN5 Q9NZD6 E1P531 A8K204 Q86Y70 Q9BY56 |
Accessions | EAW48831 EAW48832 EAW48833 EAW48834 EAW48835 Q9NUN5 AB074281 AF113224 AAG39295 AF208863 AAF64277 AF211480 AAK26247 AK002102 BAA92087 AK021916 AK225187 AK225537 AK290069 BAF82758 AY136817 AAN11301 BC010360 AAH10360 BC047073 AAH47073 BJ995961 BX647737 DA028310 XM_006715511 XP_006715574 XM_011535941 XP_011534243 NM_018368 NP_060838 |
Function | Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. Isoform 3 may play a role in the assembly of hepatitis delta virus (HDV). {ECO:0000269|PubMed:15956556, ECO:0000269|PubMed:19136951}. |
Subcellular Location | Lysosome membrane {ECO:0000269|PubMed:19136951}; Multi-pass membrane protein {ECO:0000269|PubMed:19136951}. |
Tissue Specificity | Isoform 3 is expressed in liver. {ECO:0000269|PubMed:15956556}. |
Top Pathways | Vitamin digestion and absorption |
LMBRD1 CRISPR/Cas9 KO Plasmid (h) - sc-412608 from Santa Cruz Biotechnology
|
||||||||
LMBRD1 HDR Plasmid (h) - sc-412608-HDR from Santa Cruz Biotechnology
|
||||||||
LMBRD1 Double Nickase Plasmid (h) - sc-412608-NIC from Santa Cruz Biotechnology
|
||||||||
LMBRD1 Double Nickase Plasmid (h2) - sc-412608-NIC-2 from Santa Cruz Biotechnology
|
||||||||
LMBRD1 CRISPR Activation Plasmid (h) - sc-412608-ACT from Santa Cruz Biotechnology
|
||||||||
LMBRD1 CRISPR Activation Plasmid (h2) - sc-412608-ACT-2 from Santa Cruz Biotechnology
|
||||||||
LMBRD1 Lentiviral Activation Particles (h) - sc-412608-LAC from Santa Cruz Biotechnology
|
||||||||
LMBRD1 Lentiviral Activation Particles (h2) - sc-412608-LAC-2 from Santa Cruz Biotechnology
|
||||||||
LMBRD1 siRNA (h) - sc-95260 from Santa Cruz Biotechnology
|
||||||||
LMBRD1 shRNA Plasmid (h) - sc-95260-SH from Santa Cruz Biotechnology
|
||||||||
LMBRD1 shRNA (h) Lentiviral Particles - sc-95260-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU035661 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN11765 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11765 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR02456 from Sigma-Aldrich
|
||||||||
LMBRD1 siRNA (Human) - CRJ0922 from Cohesion Biosciences
|
||||||||
Human LMBRD1 siRNA - orb271423 from Biorbyt
|
||||||||
LMBRD1 shRNA Plasmid (Human) - CHJ0922 from Cohesion Biosciences
|
||||||||
LMBRD1 miRNA 3'UTR clone - MiUTR3H-12519 from Creative biogene
|