TNFRSF13C

Gene Symbol TNFRSF13C
Entrez Gene 115650
Alt Symbol BAFF-R, BAFFR, BROMIX, CD268, CVID4, prolixin
Species Human
Gene Type protein-coding
Description tumor necrosis factor receptor superfamily, member 13C
Other Description B cell-activating factor receptor|B-cell-activating factor receptor|BAFF receptor|BLyS receptor 3|tumor necrosis factor receptor superfamily member 13C
Swissprots Q96RJ3
Accessions ABK41893 BAE16554 CAZ39524 CBF13296 CBH32711 CBH51798 CBI12201 CBI67648 CBX33268 CDG23825 EAW60473 Q96RJ3 AF373846 AAK91826 AX772914 CAE06271 AX800072 CAE51828 BC105123 AAI05124 BC111585 AAI11586 BC112030 AAI12031 NM_052945 NP_443177
Function B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. {ECO:0000269|PubMed:11591325, ECO:0000269|PubMed:12387744}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}.
Tissue Specificity Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes.
Top Pathways Cytokine-cytokine receptor interaction, Primary immunodeficiency, Intestinal immune network for IgA production, HTLV-I infection

Active human BAFF Receptor full length protein - ab191716 from Abcam

Category Protein
Prices $192.00
Sizes 50 µg
Source E. coli
Species Human

Active human BAFF Receptor protein fragment - ab157066 from Abcam

Category Protein
Prices $410.00
Sizes 50 µg
Source HEK 293 cells
Species Human
ab157066 used to show rhBAFF-R:Fc inhibits rhsBAFF-mediated activation of freshly isolated mouse splenocytes.

BAFF Receptor protein (Fc Chimera Active) - ab83931 from Abcam

Category Protein
Prices $315.00
Sizes 25 µg
Source HEK 293 cells
Species Human
Lane 1 – MW markers; Lane 2 – ab83931; Lane 3 – ab83931 treated with PNGase F to remove potential N-linked glycans; Lane 4 – ab83931 treated with a glycosidase cocktail to remove potential N- and O-linked glycans. 3 μg of protein was loaded per lane. Gels were stained with Coomassie G250. Drop in MW after treatment with PNGase F indicates the presence of N-linked glycans. A subsequent drop in MW after treatment with a glycosidase cocktail indicates O-linked glycans are also present. Additional high MW bands in lane 4 are glycosidase enzymes.

Active human BAFF Receptor protein fragment - ab50233 from Abcam

Category Protein
Prices $110.00, $200.00
Sizes 10 µg, 50 µg
Source E. coli
Species Human

Active human BAFF Receptor protein fragment - ab200303 from Abcam

Category Protein
Prices $101.00
Sizes 10 µg
Source E. coli
Species Human

Active human BAFF Receptor protein fragment - ab55757 from Abcam

Category Protein
Prices $315.00
Sizes 50 µg
Source E. coli
Species Human

Active mouse BAFF Receptor protein fragment - ab157042 from Abcam

Category Protein
Prices $410.00
Sizes 50 µg
Source HEK 293 cells
Species Mouse
Inhibition of BAFF-mediated splenocyte survival. ab157042 inhibits BAFF-mediated activation of freshly isolated splenocytes. Concentration of ab157042 to achieve complete inhibition depends on the concentration of soluble BAFF used. A ratio (soluble BAFF:ab157042) 1:50 and higher is recommended. Method: On day 0 splenocytes were isolated from a freshly collected C57Bl6 spleen. An aliquot of the splenocytes was analyzed on FACS, and B cells were gated on the SSC-FSC panel. FACS settings were saved. The rest of the cells was put in culture with media alone, with the indicated concentration of recombinant Human soluble BAFF alone or in the presence of an excess of ab157042 (50µg/ml). After three days in culture, cells were again analyzed on FACS with the saved setting. Splenocytes survival index (=ratio of %living/%dead cells) was calculated and plotted.

Human BAFF Receptor full length protein - ab132005 from Abcam

Category Protein
Prices $402.00
Sizes 10 µg
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab132005 stained with Coomassie Blue.

Human BAFF Receptor peptide - ab6086 from Abcam

Category Peptide
Prices $181.00
Sizes 50 µg
Species Human

BAFF Receptor Antibody Blocking Peptide - LS-E2913 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

BAFF Receptor Antibody Blocking Peptide - LS-E23209 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

BAFF Receptor Antibody Blocking Peptide - LS-E30010 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

Recombinant Human BAFF Receptor Protein - NBP2-34879 from Novus Biologicals

Category Protein
Prices $69.00, $169.00, $1,299.00
Sizes 10 µg, 50 µg, 1 mg
Source E. coli
Species Human

BAFF Receptor Recombinant Protein - H00115650-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

BAFF Receptor Recombinant Protein - P3588 from Novus Biologicals

Category Protein
Prices $449.00
Sizes 50 µg
Species Human

BAFF Receptor Blocking Peptide - NBP1-77234PEP from Novus Biologicals

Category Peptide
Prices $129.00
Sizes 50 µg
Species Human

BAFF Receptor Protein - NBP1-99155 from Novus Biologicals

Category Protein
Species Human

Recombinant Human BAFF Receptor Protein - NBP1-99410 from Novus Biologicals

Category Protein
Prices $190.00
Sizes 50 µg
Source E. coli
Species Human

BAFF Receptor Recombinant Protein - H00115650-G01 from Novus Biologicals

Category Protein
Prices $579.00
Sizes 10 µg
Species Human

TNFRSF13C-Antibody-N-term-Blocking-peptide - BP14039a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

BAFF Receptor recombinant protein - GTX65456 from GeneTex

Category Protein
Prices $249.00
Sizes 10 μg
Source E. coli
Species Human

BAFF Receptor Recombinant Protein (Active) - GTX48244-PRO from GeneTex

Category Protein
Prices $299.00
Sizes 50 μg
Source E. coli
Species Human

BAFF Receptor peptide - GTX26086 from GeneTex

Category Peptide
Prices $179.00
Sizes 50 μg
Species Human

Recombinant Human BAFF R/TNFRSF13C Fc Chimera, CF - 1162-BR-050 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived

BAFF R Protein (OPPA00688) - OPPA00688 from Aviva Systems Biology

Category Protein
Prices $100.00
Sizes 10 µg
Source E. Coli
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