| Gene Symbol |
UBR7
|
| Entrez Gene |
55148
|
| Alt Symbol |
C14orf130
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ubiquitin protein ligase E3 component n-recognin 7 (putative)
|
| Other Description |
N-recognin-7|putative E3 ubiquitin-protein ligase UBR7
|
| Swissprots |
Q96BY0 Q9NVV6 Q86UA9 Q86U21 Q8N806
|
| Accessions |
EAW81521 EAW81522 EAW81523 Q8N806 AK001345 BAA91639 AK097477 BAC05069 AK315492 BAG37876 BC015046 AAH15046 BC017013 AAH17013 BC051819 AAH51819 BX248249 CAD62577 DA158479 DB047433 NM_001100417 NM_175748 NP_786924 NR_038150
|
| Function |
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Expressed in sperm (at protein level). {ECO:0000269|PubMed:24664117}.
|