Gene Symbol | UBR7 |
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Entrez Gene | 55148 |
Alt Symbol | C14orf130 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
Other Description | N-recognin-7|putative E3 ubiquitin-protein ligase UBR7 |
Swissprots | Q96BY0 Q9NVV6 Q86UA9 Q86U21 Q8N806 |
Accessions | EAW81521 EAW81522 EAW81523 Q8N806 AK001345 BAA91639 AK097477 BAC05069 AK315492 BAG37876 BC015046 AAH15046 BC017013 AAH17013 BC051819 AAH51819 BX248249 CAD62577 DA158479 DB047433 NM_001100417 NM_175748 NP_786924 NR_038150 |
Function | E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity). {ECO:0000250}. |
Tissue Specificity | Expressed in sperm (at protein level). {ECO:0000269|PubMed:24664117}. |
Ubr7 CRISPR/Cas9 KO Plasmid (h) - sc-408706 from Santa Cruz Biotechnology
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Ubr7 HDR Plasmid (h) - sc-408706-HDR from Santa Cruz Biotechnology
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Ubr7 Double Nickase Plasmid (h) - sc-408706-NIC from Santa Cruz Biotechnology
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Ubr7 Double Nickase Plasmid (h2) - sc-408706-NIC-2 from Santa Cruz Biotechnology
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Ubr7 CRISPR Activation Plasmid (h) - sc-408706-ACT from Santa Cruz Biotechnology
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Ubr7 CRISPR Activation Plasmid (h2) - sc-408706-ACT-2 from Santa Cruz Biotechnology
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Ubr7 Lentiviral Activation Particles (h) - sc-408706-LAC from Santa Cruz Biotechnology
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Ubr7 Lentiviral Activation Particles (h2) - sc-408706-LAC-2 from Santa Cruz Biotechnology
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Ubr7 siRNA (h) - sc-92200 from Santa Cruz Biotechnology
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Ubr7 shRNA Plasmid (h) - sc-92200-SH from Santa Cruz Biotechnology
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Ubr7 shRNA (h) Lentiviral Particles - sc-92200-V from Santa Cruz Biotechnology
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UBR7 RNAi - H00055148-R01 from Novus Biologicals
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UBR7 RNAi - H00055148-R02 from Novus Biologicals
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MISSION® esiRNA - EHU031991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22419 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22419 from Sigma-Aldrich
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UBR7 siRNA (Human) - CRJ0505 from Cohesion Biosciences
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UBR7 - MBS8229190 from MyBioSource
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shRNA set against Human UBR7 (NM_175748.3) - SHH439576 from Creative biogene
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Human UBR7 siRNA - orb271006 from Biorbyt
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UBR7 shRNA Plasmid (Human) - CHJ0505 from Cohesion Biosciences
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UBR7 miRNA 3'UTR clone - MiUTR1H-01094 from Creative biogene
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