MMP16

Gene Symbol MMP16
Entrez Gene 4325
Alt Symbol C8orf57, MMP-X2, MT-MMP2, MT-MMP3, MT3-MMP
Species Human
Gene Type protein-coding
Description matrix metallopeptidase 16 (membrane-inserted)
Other Description MMP-16|MT-MMP 3|MT3MMP|MTMMP3|Putative transmembrane protein C8orf57|matrix metalloproteinase-16|membrane-type matrix metalloproteinase 3|membrane-type-3 matrix metalloproteinase
Swissprots Q52H48 P51512 Q14824 B2RAN7
Accessions AAX84515 EAW91651 EAW91652 P51512 AB009303 BAA23742 AK314274 BAG36934 AL136588 CAB66523 AL832595 BC069500 AAH69500 BC075004 AAH75004 BC075005 AAH75005 D83646 BAA12022 D83647 BAA12023 D85511 BAA22226 DA575789 DR002176 U79292 XM_011517039 XP_011515341 XM_011517040 XP_011515342 XM_011517041 XP_011515343 XM_011517042 XP_011515344 XR_928334 NM_005941 NP_005932 NM_022564 NM_032297
Function Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells. {ECO:0000269|PubMed:11278606}.
Subcellular Location Isoform Long: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}; Extracellular side {ECO:0000305}. Note=Localized at the cell surface of melanoma cells.
Tissue Specificity Expressed in heart, brain, placenta, ovary and small intestine. Isoform Short is found in the ovary.
Top Pathways MicroRNAs in cancer

MMP16 peptide - ab41099 from Abcam

Category Peptide

MMP16 peptide - ab43114 from Abcam

Category Peptide

MMP16 peptide - ab44857 from Abcam

Category Peptide

MMP16 Antibody Blocking Peptide - LS-E2642 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

MMP16 Antibody Blocking Peptide - LS-E16985 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human MMP-16/MT3-MMP Protein - P4927 from Novus Biologicals

Category Protein
Prices $1,049.00
Sizes 10 µg
Source E. coli
Species Human

MMP16-Antibody-C-term-Blocking-peptide - BP13713b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human MMP-16/MT3-MMP, CF - 1785-MP-010 from R&D Systems

Category Protein
Source E. coli-derived, Ala32-Gly291 (Ile152Asn), with a C-terminal 10-His tag

MMP16 peptide - orb219135 from Biorbyt

Category Peptide
Prices $272.00, $510.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Rabbit, Chicken, Monkey, Dog, Pig

MMP16 Blocking Peptide - 33R-1318 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

Human MMP16 Protein - abx067960 from Abbexa

Category Protein
Source E.coli
Species Human

MMP16 Blocking Peptide - abx062166 from Abbexa

Category Peptide
Species Human, Mouse, Rat, Bovine, Chicken, Dog, Monkey, Pig, Rabbit

MMP-16 - P4927 from Acris Antibodies

Category Protein
Prices $750.00
Sizes 10 µg
Species Human

MMP16 fusion protein - ag12186 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

MMP16 fusion protein - Ag12719 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human MMP16, Catalytic Domain - MMP16-608H from Creative Biomart

Category Protein
Source E. coli .

Recombinant Matrix Metalloproteinase 16 (MMP16) - RPB533Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

MMP16 Blocking Peptide - CBP3272 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Bovine, Chicken, Dog, Monkey, Pig, Rabbit

MMP-16 (T583) Peptide - BS1234P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl

Recombinant Matrix Metalloproteinase 16 (MMP16) - RPB533Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human Matrix metalloproteinase-16(MMP16) - CSB-YP014663HU CSB-EP014663HU CSB-BP014663HU CSB-MP014663HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Human MMP-16/MT3-MMP Protein, CF - 1785-MP from R&D Systems

Category Protein
Prices $329.00
Sizes 10 µg
Source E. coli -derived Ala32-Gly291 (Ile152Asn), with a C-terminal 10-His tag
Species Human

MMP16-Antibody-N-term-Blocking-Peptide - BP6200a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

MMP16 Peptide, Human - M34GP09596H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

MMP16 Recombinant Protein (OPCD05328) - OPCD05328 from Aviva Systems Biology

Category Protein
Source E.coli
Species Human
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