| Gene Symbol |
SOD3
|
| Entrez Gene |
6649
|
| Alt Symbol |
EC-SOD
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
superoxide dismutase 3, extracellular
|
| Other Description |
extracellular superoxide dismutase [Cu-Zn]
|
| Swissprots |
Q6FHA2 Q5U781 P08294
|
| Accessions |
AAA62278 AAB31336 AAV40827 EAW92823 P08294 AK313935 BAG36654 BC014418 AAH14418 BI757365 BM677660 CR541853 CAG46651 DA668533 DQ892086 ABM83012 DQ895280 ABM86206 J02947 AAA66000 XR_427488 NM_003102 NP_003093
|
| Function |
Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
|
| Subcellular Location |
Secreted, extracellular space. Note=99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium.
|
| Tissue Specificity |
Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.
|
![Western Blot: Superoxide Dismutase 3 Overexpression Lysate (Adult Normal) [NBL1-16335] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Superoxide Dismutase 3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6950_Superoxide%2520Dismutase%25203%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16335-img0002.jpg)