Gene Symbol | SOD3 |
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Entrez Gene | 6649 |
Alt Symbol | EC-SOD |
Species | Human |
Gene Type | protein-coding |
Description | superoxide dismutase 3, extracellular |
Other Description | extracellular superoxide dismutase [Cu-Zn] |
Swissprots | Q6FHA2 Q5U781 P08294 |
Accessions | AAA62278 AAB31336 AAV40827 EAW92823 P08294 AK313935 BAG36654 BC014418 AAH14418 BI757365 BM677660 CR541853 CAG46651 DA668533 DQ892086 ABM83012 DQ895280 ABM86206 J02947 AAA66000 XR_427488 NM_003102 NP_003093 |
Function | Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. |
Subcellular Location | Secreted, extracellular space. Note=99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium. |
Tissue Specificity | Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid. |
SOD-3 CRISPR/Cas9 KO Plasmid (h) - sc-402505 from Santa Cruz Biotechnology
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SOD-3 HDR Plasmid (h) - sc-402505-HDR from Santa Cruz Biotechnology
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SOD-3 Double Nickase Plasmid (h) - sc-402505-NIC from Santa Cruz Biotechnology
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SOD-3 Double Nickase Plasmid (h2) - sc-402505-NIC-2 from Santa Cruz Biotechnology
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SOD-3 CRISPR Activation Plasmid (h) - sc-402505-ACT from Santa Cruz Biotechnology
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SOD-3 CRISPR Activation Plasmid (h2) - sc-402505-ACT-2 from Santa Cruz Biotechnology
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SOD-3 Lentiviral Activation Particles (h) - sc-402505-LAC from Santa Cruz Biotechnology
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SOD-3 Lentiviral Activation Particles (h2) - sc-402505-LAC-2 from Santa Cruz Biotechnology
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SOD-3 siRNA (h) - sc-44699 from Santa Cruz Biotechnology
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SOD-3 shRNA Plasmid (h) - sc-44699-SH from Santa Cruz Biotechnology
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SOD-3 shRNA (h) Lentiviral Particles - sc-44699-V from Santa Cruz Biotechnology
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SOD3/EC-SOD RNAi - H00006649-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN20328 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20328 from Sigma-Aldrich
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SOD3 siRNA (Human) - CRH4529 from Cohesion Biosciences
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SOD3 - MBS8233144 from MyBioSource
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shRNA set against Human SOD3 (NM_003102.2) - SHH415044 from Creative biogene
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shRNA set against Human SOD3(NM_003102.2) - SHL024654 from Creative biogene
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Human SOD3 siRNA - orb265031 from Biorbyt
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SOD3 shRNA Plasmid (Human) - CHH4529 from Cohesion Biosciences
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SOD3 miRNA 3'UTR clone - MiUTR1H-09739 from Creative biogene
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