| Gene Symbol |
FBXO25
|
| Entrez Gene |
26260
|
| Alt Symbol |
FBX25
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
F-box protein 25
|
| Other Description |
F-box only protein 25|F-box protein Fbx25
|
| Swissprots |
Q9UKB8 Q8TCJ0 Q7Z4V4 Q6PJ83
|
| Accessions |
EAW51450 EAW51451 EAW51452 EAW51453 EAW51454 EAW51455 Q8TCJ0 AA316216 AB070270 BAB85128 AF174605 AAF04526 AF419858 AAP97293 AI223050 AK302334 BAG63665 BC012143 BC020249 AAH20249 BC035555 BC050393 AAH50393 DQ586074 HQ447709 ADQ32194 XM_005266029 XP_005266086 XM_005266030 XP_005266087 XM_005266031 XP_005266088 XM_005266032 XP_005266089 XM_005266033 XP_005266090 XM_011534748 XP_011533050 XM_011534749 XP_011533051 NM_012173 NP_036305 NM_183420 NP_904356 NM_183421 NP_904357
|
| Function |
Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:16278047, ECO:0000269|PubMed:18287534}. Note=In the nucleus, associates with a subnuclear dot-like structure. Colocalized with SKP1.
|
| Tissue Specificity |
Expressed in all brain tissue observed. {ECO:0000269|PubMed:16278047}.
|
![Western Blot: FBXO25 Overexpression Lysate (Adult Normal) [NBL1-10625] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for FBXO25.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/7853_FBXO25%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-10625-img0002.jpg)
![Western Blot: FBXO25 Overexpression Lysate (Adult Normal) [NBP2-07486] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for FBXO25.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5759_FBXO25%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07486-img0001.jpg)