| Gene Symbol | GUCA1C |
|---|---|
| Entrez Gene | 9626 |
| Alt Symbol | GCAP3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | guanylate cyclase activator 1C |
| Other Description | GCAP 3|guanylyl cyclase-activating protein 3 |
| Swissprots | Q9UNM0 O95843 O95844 |
| Accessions | AAD19943 EAW79715 EAW79716 O95843 AB593147 BAJ84081 AF110002 AAD19944 AF110003 AAD19945 AV732101 BC103993 AAI03994 BC103994 AAI03995 C20850 EU832759 ACE87770 GQ129299 ACT64433 XM_005247910 XP_005247967 XM_011513334 XP_011511636 NM_005459 NP_005450 |
| Function | Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)- sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure. |
| Tissue Specificity | Retina. |
| Top Pathways | Olfactory transduction, Phototransduction |