Gene Symbol |
GUCA1C
|
Entrez Gene |
9626
|
Alt Symbol |
GCAP3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
guanylate cyclase activator 1C
|
Other Description |
GCAP 3|guanylyl cyclase-activating protein 3
|
Swissprots |
Q9UNM0 O95843 O95844
|
Accessions |
AAD19943 EAW79715 EAW79716 O95843 AB593147 BAJ84081 AF110002 AAD19944 AF110003 AAD19945 AV732101 BC103993 AAI03994 BC103994 AAI03995 C20850 EU832759 ACE87770 GQ129299 ACT64433 XM_005247910 XP_005247967 XM_011513334 XP_011511636 NM_005459 NP_005450
|
Function |
Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)- sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.
|
Tissue Specificity |
Retina.
|
Top Pathways |
Olfactory transduction, Phototransduction
|