Gene Symbol |
PLEKHA3
|
Entrez Gene |
65977
|
Alt Symbol |
FAPP1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
|
Other Description |
FAPP-1|PH domain-containing family A member 3|four-phosphate-adaptor protein 1|phosphatidylinositol-four-phosphate adapter protein 1|phosphoinositol 4-phosphate adapter protein 1|pleckstrin homology domain-containing family A member 3|pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3
|
Swissprots |
Q9NXT3 Q4ZG69 Q86TQ1 Q9HB20
|
Accessions |
AAX88884 EAX11023 EAX11024 EAX11025 EAX11026 Q9HB20 AF286162 AAG15199 AK000074 BAA90927 AK074209 AK314459 BAG37067 BC035471 BC039812 BC044567 AAH44567 BM794932 DQ786259 DQ786318 EU832321 ACE87578 EU832406 ACE86891 XM_011511689 XP_011509991 NM_019091 NP_061964
|
Function |
Involved in Golgi to cell surface membrane traffic. Induces membrane tubulation. Binds preferentially to phosphatidylinositol 4-phosphate (PtdIns4P). {ECO:0000269|PubMed:15107860}.
|
Subcellular Location |
Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:15107860}; Peripheral membrane protein {ECO:0000269|PubMed:15107860}.
|
Tissue Specificity |
Widely expressed.
|