Gene Symbol | PLEKHA3 |
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Entrez Gene | 65977 |
Alt Symbol | FAPP1 |
Species | Human |
Gene Type | protein-coding |
Description | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 |
Other Description | FAPP-1|PH domain-containing family A member 3|four-phosphate-adaptor protein 1|phosphatidylinositol-four-phosphate adapter protein 1|phosphoinositol 4-phosphate adapter protein 1|pleckstrin homology domain-containing family A member 3|pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3 |
Swissprots | Q9NXT3 Q4ZG69 Q86TQ1 Q9HB20 |
Accessions | AAX88884 EAX11023 EAX11024 EAX11025 EAX11026 Q9HB20 AF286162 AAG15199 AK000074 BAA90927 AK074209 AK314459 BAG37067 BC035471 BC039812 BC044567 AAH44567 BM794932 DQ786259 DQ786318 EU832321 ACE87578 EU832406 ACE86891 XM_011511689 XP_011509991 NM_019091 NP_061964 |
Function | Involved in Golgi to cell surface membrane traffic. Induces membrane tubulation. Binds preferentially to phosphatidylinositol 4-phosphate (PtdIns4P). {ECO:0000269|PubMed:15107860}. |
Subcellular Location | Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:15107860}; Peripheral membrane protein {ECO:0000269|PubMed:15107860}. |
Tissue Specificity | Widely expressed. |
FAPP1 CRISPR/Cas9 KO Plasmid (h) - sc-418005 from Santa Cruz Biotechnology
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FAPP1 HDR Plasmid (h) - sc-418005-HDR from Santa Cruz Biotechnology
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FAPP1 Double Nickase Plasmid (h) - sc-418005-NIC from Santa Cruz Biotechnology
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FAPP1 Double Nickase Plasmid (h2) - sc-418005-NIC-2 from Santa Cruz Biotechnology
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FAPP1 CRISPR Activation Plasmid (h) - sc-418005-ACT from Santa Cruz Biotechnology
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FAPP1 CRISPR Activation Plasmid (h2) - sc-418005-ACT-2 from Santa Cruz Biotechnology
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FAPP1 Lentiviral Activation Particles (h) - sc-418005-LAC from Santa Cruz Biotechnology
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FAPP1 Lentiviral Activation Particles (h2) - sc-418005-LAC-2 from Santa Cruz Biotechnology
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FAPP1 siRNA (h) - sc-94848 from Santa Cruz Biotechnology
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FAPP1 shRNA Plasmid (h) - sc-94848-SH from Santa Cruz Biotechnology
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FAPP1 shRNA (h) Lentiviral Particles - sc-94848-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU041031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16948 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16948 from Sigma-Aldrich
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PLEKHA3 siRNA (Human) - CRJ2206 from Cohesion Biosciences
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shRNA set against Human PLEKHA3 (NM_019091.3) - SHH377472 from Creative biogene
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shRNA set against Human PLEKHA3(NM_019091.3) - SHR121728 from Creative biogene
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Human PLEKHA3 siRNA - orb272707 from Biorbyt
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PLEKHA3 shRNA Plasmid (Human) - CHJ2206 from Cohesion Biosciences
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PLEKHA3 miRNA 3'UTR clone - MiUTR1H-07996 from Creative biogene
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