| Gene Symbol |
SEMA3C
|
| Entrez Gene |
10512
|
| Alt Symbol |
SEMAE, SemE
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
|
| Other Description |
sema E|semaphorin E|semaphorin-3C|semaphorin-E
|
| Swissprots |
B4DRL8 Q99985
|
| Accessions |
AAS00351 AAS07489 CAI84573 EAL24190 EAW76995 Q99985 AA853650 AB000220 BAA32398 AF086506 AK299322 BAG61330 AK304294 BAG65151 AK312478 BAG35382 AL135601 BC030690 AAH30690 BF983184 BI494187 BM473251 BU740462 CN334967 CN334969 D32000 DQ890847 ABM81773 DQ894001 ABM84927 LN626689 CEH24704 XM_005250113 XP_005250170 NM_006379 NP_006370
|
| Function |
Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Expressed intensely in the heart, skeletal muscle, colon, small intestine, ovary, testis, and prostate. Faint expression ubiquitously among other organs, including brain.
|
| Top Pathways |
Axon guidance
|
![Western Blot: SEMA3C Overexpression Lysate (Adult Normal) [NBL1-15799] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SEMA3C.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8183_SEMA3C%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15799-img0002.jpg)