Gene Symbol | SEMA3C |
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Entrez Gene | 10512 |
Alt Symbol | SEMAE, SemE |
Species | Human |
Gene Type | protein-coding |
Description | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
Other Description | sema E|semaphorin E|semaphorin-3C|semaphorin-E |
Swissprots | B4DRL8 Q99985 |
Accessions | AAS00351 AAS07489 CAI84573 EAL24190 EAW76995 Q99985 AA853650 AB000220 BAA32398 AF086506 AK299322 BAG61330 AK304294 BAG65151 AK312478 BAG35382 AL135601 BC030690 AAH30690 BF983184 BI494187 BM473251 BU740462 CN334967 CN334969 D32000 DQ890847 ABM81773 DQ894001 ABM84927 LN626689 CEH24704 XM_005250113 XP_005250170 NM_006379 NP_006370 |
Function | Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed intensely in the heart, skeletal muscle, colon, small intestine, ovary, testis, and prostate. Faint expression ubiquitously among other organs, including brain. |
Top Pathways | Axon guidance |
SEMA3C CRISPR/Cas9 KO Plasmid (h) - sc-402489 from Santa Cruz Biotechnology
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SEMA3C HDR Plasmid (h) - sc-402489-HDR from Santa Cruz Biotechnology
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SEMA3C Double Nickase Plasmid (h) - sc-402489-NIC from Santa Cruz Biotechnology
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SEMA3C Double Nickase Plasmid (h2) - sc-402489-NIC-2 from Santa Cruz Biotechnology
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SEMA3C CRISPR Activation Plasmid (h) - sc-402489-ACT from Santa Cruz Biotechnology
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SEMA3C CRISPR Activation Plasmid (h2) - sc-402489-ACT-2 from Santa Cruz Biotechnology
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SEMA3C Lentiviral Activation Particles (h) - sc-402489-LAC from Santa Cruz Biotechnology
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SEMA3C Lentiviral Activation Particles (h2) - sc-402489-LAC-2 from Santa Cruz Biotechnology
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SEMA3C siRNA (h) - sc-44091 from Santa Cruz Biotechnology
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SEMA3C shRNA Plasmid (h) - sc-44091-SH from Santa Cruz Biotechnology
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SEMA3C shRNA (h) Lentiviral Particles - sc-44091-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU026041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19065 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19065 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11510 from Sigma-Aldrich
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SEMA3C siRNA (Human) - CRH7140 from Cohesion Biosciences
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SEMA3C - MBS8207767 from MyBioSource
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shRNA set against Human SEMA3C (NM_006379.3) - SHH404208 from Creative biogene
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SEMA3C shRNA Plasmid (Human) - CHH7140 from Cohesion Biosciences
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SEMA3C miRNA 3'UTR clone - MiUTR4H-TG07902 from Creative biogene
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