| Gene Symbol |
VAV1
|
| Entrez Gene |
7409
|
| Alt Symbol |
VAV
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
vav 1 guanine nucleotide exchange factor
|
| Other Description |
proto-oncogene vav|vav 1 oncogene
|
| Swissprots |
M0QXX6 B4DVK9 Q15860 P15498
|
| Accessions |
AAA63267 AAC25011 CCO13847 EAW69057 EAW69058 P15498 AK225710 AK301128 BAG62721 AK313307 BAG36112 AW105491 BC013361 AAH13361 DC408645 X16316 CAA34383 X83931 CAA58783 XM_005259642 XP_005259699 XM_011528254 XP_011526556 NM_001258206 NP_001245135 NM_001258207 NP_001245136 NM_005428 NP_005419
|
| Function |
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
|
| Tissue Specificity |
Widely expressed in hematopoietic cells but not in other cell types.
|
| Top Pathways |
cAMP signaling pathway, Focal adhesion, Chemokine signaling pathway, Fc gamma R-mediated phagocytosis, Leukocyte transendothelial migration
|
![Western Blot: VAV1 Overexpression Lysate (Adult Normal) [NBL1-17701] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for VAV1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5386_VAV1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17701-img0002.jpg)