Gene Symbol | VAV1 |
---|---|
Entrez Gene | 7409 |
Alt Symbol | VAV |
Species | Human |
Gene Type | protein-coding |
Description | vav 1 guanine nucleotide exchange factor |
Other Description | proto-oncogene vav|vav 1 oncogene |
Swissprots | M0QXX6 B4DVK9 Q15860 P15498 |
Accessions | AAA63267 AAC25011 CCO13847 EAW69057 EAW69058 P15498 AK225710 AK301128 BAG62721 AK313307 BAG36112 AW105491 BC013361 AAH13361 DC408645 X16316 CAA34383 X83931 CAA58783 XM_005259642 XP_005259699 XM_011528254 XP_011526556 NM_001258206 NP_001245135 NM_001258207 NP_001245136 NM_005428 NP_005419 |
Function | Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation. |
Tissue Specificity | Widely expressed in hematopoietic cells but not in other cell types. |
Top Pathways | cAMP signaling pathway, Focal adhesion, Chemokine signaling pathway, Fc gamma R-mediated phagocytosis, Leukocyte transendothelial migration |
Vav CRISPR/Cas9 KO Plasmid (h) - sc-400606 from Santa Cruz Biotechnology
|
||||||||
Vav HDR Plasmid (h) - sc-400606-HDR from Santa Cruz Biotechnology
|
||||||||
Vav Double Nickase Plasmid (h) - sc-400606-NIC from Santa Cruz Biotechnology
|
||||||||
Vav Double Nickase Plasmid (h2) - sc-400606-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Vav CRISPR Activation Plasmid (h) - sc-400606-ACT from Santa Cruz Biotechnology
|
||||||||
Vav CRISPR Activation Plasmid (h2) - sc-400606-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Vav Lentiviral Activation Particles (h) - sc-400606-LAC from Santa Cruz Biotechnology
|
||||||||
Vav Lentiviral Activation Particles (h2) - sc-400606-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Vav siRNA (h) - sc-29517 from Santa Cruz Biotechnology
|
||||||||
Vav shRNA Plasmid (h) - sc-29517-SH from Santa Cruz Biotechnology
|
||||||||
Vav shRNA (h) Lentiviral Particles - sc-29517-V from Santa Cruz Biotechnology
|
||||||||
Vav-1 RNAi - H00007409-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU048531 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN1075 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1075 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR02247 from Sigma-Aldrich
|
||||||||
VAV1 siRNA (Human) - CRH5068 from Cohesion Biosciences
|
||||||||
VAV1 - MBS8210329 from MyBioSource
|
||||||||
Vav CRISPR/Cas9 KO Plasmid (h2) - sc-400606-KO-2 from Santa Cruz Biotechnology
|
||||||||
Vav HDR Plasmid (h2) - sc-400606-HDR-2 from Santa Cruz Biotechnology
|
||||||||
shRNA set against Human VAV1 (NM_005428.3) - SHH442352 from Creative biogene
|
||||||||
Human VAV1 siRNA - orb265570 from Biorbyt
|
||||||||
VAV1 shRNA Plasmid (Human) - CHH5068 from Cohesion Biosciences
|
||||||||
VAV1 miRNA 3'UTR clone - MiUTR3H-01611 from Creative biogene
|