| Gene Symbol |
CLECL1
|
| Entrez Gene |
160365
|
| Alt Symbol |
DCAL-1, DCAL1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
C-type lectin-like 1
|
| Other Description |
C-type lectin-like domain family 1|DC-associated lectin-1|dendritic cell associated lectin 1|dendritic cell-associated lectin 1|dendritic cell-associated lectin-1|type II transmembrane protein DCAL1
|
| Swissprots |
Q8IZS7
|
| Accessions |
CCF76983 EAW96120 EAW96121 Q8IZS7 AF518873 AAN64752 AW237307 BC042176 BC093857 AAH93857 BC093859 AAH93859 BX103210 DA619574 XM_011520574 XP_011518876 NM_001253750 NP_001240679 NM_001267701 NP_001254630 NM_172004 NP_742001
|
| Function |
May function in mediating immune cell-cell interactions. May act as a T-cell costimulatory molecule, enhancing anti-CD3- induced proliferation. May play a role in the interaction of dendritic cells with T-cells and the cells of the adaptive immune response. {ECO:0000269|PubMed:12421943}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:12421943}; Single-pass type II membrane protein {ECO:0000269|PubMed:12421943}.
|
| Tissue Specificity |
Expressed in spleen, lymph node, and tonsil. Lower expression in peripheral blood, bone marrow, and colon. No expression detected in thymus. Highly expressed in dendritic and B-cells. {ECO:0000269|PubMed:12421943}.
|