Gene Symbol | CLECL1 |
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Entrez Gene | 160365 |
Alt Symbol | DCAL-1, DCAL1 |
Species | Human |
Gene Type | protein-coding |
Description | C-type lectin-like 1 |
Other Description | C-type lectin-like domain family 1|DC-associated lectin-1|dendritic cell associated lectin 1|dendritic cell-associated lectin 1|dendritic cell-associated lectin-1|type II transmembrane protein DCAL1 |
Swissprots | Q8IZS7 |
Accessions | CCF76983 EAW96120 EAW96121 Q8IZS7 AF518873 AAN64752 AW237307 BC042176 BC093857 AAH93857 BC093859 AAH93859 BX103210 DA619574 XM_011520574 XP_011518876 NM_001253750 NP_001240679 NM_001267701 NP_001254630 NM_172004 NP_742001 |
Function | May function in mediating immune cell-cell interactions. May act as a T-cell costimulatory molecule, enhancing anti-CD3- induced proliferation. May play a role in the interaction of dendritic cells with T-cells and the cells of the adaptive immune response. {ECO:0000269|PubMed:12421943}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:12421943}; Single-pass type II membrane protein {ECO:0000269|PubMed:12421943}. |
Tissue Specificity | Expressed in spleen, lymph node, and tonsil. Lower expression in peripheral blood, bone marrow, and colon. No expression detected in thymus. Highly expressed in dendritic and B-cells. {ECO:0000269|PubMed:12421943}. |
CLEC-L1 CRISPR/Cas9 KO Plasmid (h) - sc-414815 from Santa Cruz Biotechnology
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CLEC-L1 HDR Plasmid (h) - sc-414815-HDR from Santa Cruz Biotechnology
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CLEC-L1 Double Nickase Plasmid (h) - sc-414815-NIC from Santa Cruz Biotechnology
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CLEC-L1 Double Nickase Plasmid (h2) - sc-414815-NIC-2 from Santa Cruz Biotechnology
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CLEC-L1 CRISPR Activation Plasmid (h) - sc-414815-ACT from Santa Cruz Biotechnology
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CLEC-L1 CRISPR Activation Plasmid (h2) - sc-414815-ACT-2 from Santa Cruz Biotechnology
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CLEC-L1 Lentiviral Activation Particles (h) - sc-414815-LAC from Santa Cruz Biotechnology
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CLEC-L1 Lentiviral Activation Particles (h2) - sc-414815-LAC-2 from Santa Cruz Biotechnology
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CLEC-L1 siRNA (h) - sc-96106 from Santa Cruz Biotechnology
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CLEC-L1 shRNA Plasmid (h) - sc-96106-SH from Santa Cruz Biotechnology
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CLEC-L1 shRNA (h) Lentiviral Particles - sc-96106-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN6226 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6226 from Sigma-Aldrich
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CLECL1 siRNA (Human) - CRJ5901 from Cohesion Biosciences
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CLECL1 - MBS8227273 from MyBioSource
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shRNA set against Human CLECL1 (NM_172004.3) - SHH265257 from Creative biogene
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Human CLECL1 siRNA - orb276402 from Biorbyt
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CLECL1 shRNA Plasmid (Human) - CHJ5901 from Cohesion Biosciences
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CLECL1 miRNA 3'UTR clone - MiUTR4H-TG02175 from Creative biogene
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