Gene Symbol | FLI1 |
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Entrez Gene | 2313 |
Alt Symbol | EWSR2, SIC-1 |
Species | Human |
Gene Type | protein-coding |
Description | Fli-1 proto-oncogene, ETS transcription factor |
Other Description | Ewing sarcoma breakpoint region 2|Friend leukemia integration 1 transcription factor|Friend leukemia virus integration 1|transcription factor ERGB |
Swissprots | Q14319 Q01543 B4DFV4 G3V183 B4DTC6 B2R8H2 Q9UE07 Q92480 |
Accessions | AAA76854 AAG33027 BAA07463 BAA32805 BAA32806 CAA76731 CDL93502 EAW67715 EAW67716 EAW67717 EAW67718 EAW67719 EAW67720 Q01543 AF147318 AI354789 AK294279 BAG57565 AK300153 BAG61938 AK313370 BAG36169 AY029368 AAK50443 BC001670 AAH01670 BC010115 AAH10115 BX647094 DC381599 DQ892582 ABM83508 DQ896858 ABM87857 M93255 AAA58479 M98833 AAA35812 S45205 AAB23637 S64709 X67001 CAA47399 XM_011542701 XP_011541003 XM_011542702 XP_011541004 NM_001167681 NP_001161153 NM_001271010 NP_001257939 NM_001271012 NP_001257941 NM_002017 NP_002008 |
Function | Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'. |
Subcellular Location | Nucleus. |
Top Pathways | Transcriptional misregulation in cancer |
Fli-1 CRISPR/Cas9 KO Plasmid (h) - sc-400494 from Santa Cruz Biotechnology
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Fli-1 HDR Plasmid (h) - sc-400494-HDR from Santa Cruz Biotechnology
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Fli-1 Double Nickase Plasmid (h) - sc-400494-NIC from Santa Cruz Biotechnology
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Fli-1 Double Nickase Plasmid (h2) - sc-400494-NIC-2 from Santa Cruz Biotechnology
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Fli-1 CRISPR Activation Plasmid (h) - sc-400494-ACT from Santa Cruz Biotechnology
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Fli-1 CRISPR Activation Plasmid (h2) - sc-400494-ACT-2 from Santa Cruz Biotechnology
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Fli-1 Lentiviral Activation Particles (h) - sc-400494-LAC from Santa Cruz Biotechnology
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Fli-1 Lentiviral Activation Particles (h2) - sc-400494-LAC-2 from Santa Cruz Biotechnology
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Fli-1 siRNA (h) - sc-35384 from Santa Cruz Biotechnology
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Fli-1 shRNA Plasmid (h) - sc-35384-SH from Santa Cruz Biotechnology
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Fli-1 shRNA (h) Lentiviral Particles - sc-35384-V from Santa Cruz Biotechnology
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FLI1 RNAi - H00002313-R01V from Novus Biologicals
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MISSION® esiRNA - EHU091961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8731 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8731 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09206 from Sigma-Aldrich
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FLI1 siRNA (Human) - CRH1618 from Cohesion Biosciences
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FLI1 RNAi - H00002313-R01 from Novus Biologicals
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FLI1 - MBS8216553 from MyBioSource
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shRNA set against Human FLI1 (NM_002017.4) - SHH295417 from Creative biogene
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Human FLI1 siRNA - orb262120 from Biorbyt
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FLI1 shRNA Plasmid (Human) - CHH1618 from Cohesion Biosciences
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FLI1 miRNA 3'UTR clone - MiUTR4H-TG03573 from Creative biogene
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