ADA

Gene Symbol ADA
Entrez Gene 100
Alt Symbol -
Species Human
Gene Type protein-coding
Description adenosine deaminase
Other Description adenosine aminohydrolase
Swissprots Q6LA59 P00813 Q53F92
Accessions AAA78791 CAA26130 CBX85542 CBX85614 EAW75904 EAW75905 EAW75906 EAW75907 P00813 AK123988 AK223397 BAD97117 AL832305 BC007678 AAH07678 BC040226 AAH40226 BI601734 DQ892681 ABM83607 DQ895924 ABM86850 KJ534760 AHW56400 S66773 AAB28742 X02994 CAA26734 XM_005260236 XP_005260293 XM_011528478 XP_011526780 XM_011528479 XP_011526781 XR_244129 NM_000022 NP_000013
Function Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte- epithelial cell adhesion. {ECO:0000269|PubMed:11772392}.
Subcellular Location Cell membrane; Peripheral membrane protein; Extracellular side. Cell junction. Cytoplasmic vesicle lumen {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Colocalized with DPP4 at the cell junction in lymphocyte-epithelial cell adhesion.
Tissue Specificity Found in all tissues, occurs in large amounts in T-lymphocytes and, at the time of weaning, in gastrointestinal tissues.
Top Pathways Primary immunodeficiency, Purine metabolism

adenosine deaminase (H-300) - sc-25747 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
adenosine deaminase (H-300): sc-25747. Immunofluorescence staining of normal mouse intestine frozen section showing cytoplasmic staining.

adenosine deaminase (D-10) - sc-376889 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
adenosine deaminase (D-10): sc-376889. Western blot analysis of adenosine deaminase expression in Jurkat whole cell lysate.

adenosine deaminase (C-20) - sc-7450 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Adenosine deaminase (C-20): sc-7450. Western blot analysis of adenosine deaminase expression in Jurkat (A) and MOLT-4 (B) whole cell lysates.

adenosine deaminase (D-4) - sc-28346 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
adenosine deaminase (D-4): sc-28346. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cerebellum tissue showing membrane staining of cells in granular and molecular layers. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

adenosine deaminase (N-19) - sc-7451 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
adenosine deaminase (N-19): sc-7451. Western blot analysis of adenosine deaminase expression in non-transfected 293T: sc-117752 (A), mouse adenosine deaminase transfected 293T: sc-126394 (B) and Jurkat (C) whole cell lysates.

Anti-ADA antibody - ab54969 from Abcam

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ADA antibody [EPR4437] - ab108254 from Abcam

Host Rabbit
Clonality Monoclonal
Clone EPR4437
All lanes : Anti-ADA antibody [EPR4437] (ab108254) at 1/1000 dilutionLane 1 : Jurkat lysatesLane 2 : Human thymus lysates Lysates/proteins at 10 µg per lane.

Anti-ADA antibody [EPR4438] - ab108352 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4438
All lanes : Anti-ADA antibody [EPR4438] (ab108352) at 1/1000 dilutionLane 1 : Jurkat cell lysateLane 2 : Human fetal thymus lysateLane 3 : Rat kidney tissue lysateLysates/proteins at 10 µg per lane.

Anti-ADA antibody - C-terminal - ab170526 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ADA antibody - C-terminal (ab170526) at 1/100 dilution + HL60 cell line lysate at 35 µg

Anti-ADA / Adenosine Deaminase Antibody - LS-C331208 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of U2OS cell using ADA antibody. Blue: DAPI for nuclear staining.

Anti-ADA / Adenosine Deaminase Antibody (aa114-148) - LS-C344697 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysates from zebra fish brain and Zebrafish tissue lysate (from left to right) with (DANRE) ada Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.

Anti-ADA / Adenosine Deaminase Antibody (aa288-337) IHC-plus™ - LS-B11947 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-ADA / Adenosine Deaminase Antibody - LS-C3557 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-ADA / Adenosine Deaminase Antibody - LS-C34887 from LifeSpan Bioscience

Prices $275.00
Sizes 10 mg
Host Rabbit
Clonality Polyclonal

Anti-ADA / Adenosine Deaminase Antibody - LS-C34886 from LifeSpan Bioscience

Prices $295.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-ADA / Adenosine Deaminase Antibody (Biotin) - LS-C34888 from LifeSpan Bioscience

Prices $265.00
Sizes 1 mg
Host Rabbit
Clonality Polyclonal

Anti-ADA / Adenosine Deaminase Antibody (HRP) - LS-C34889 from LifeSpan Bioscience

Prices $255.00
Sizes 1 mg
Host Rabbit
Clonality Polyclonal

Anti-ADA / Adenosine Deaminase Antibody - LS-C45499 from LifeSpan Bioscience

Prices $645.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ADA / Adenosine Deaminase Antibody - LS-C122612 from LifeSpan Bioscience

Prices $755.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ADA / Adenosine Deaminase Antibody - LS-C147280 from LifeSpan Bioscience

Prices $270.00
Sizes 10 mg
Host Rabbit
Clonality Polyclonal

Anti-ADA / Adenosine Deaminase Antibody (Biotin) - LS-C147281 from LifeSpan Bioscience

Prices $360.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-ADA / Adenosine Deaminase Antibody - LS-C147282 from LifeSpan Bioscience

Prices $455.00
Sizes 1 mg
Host Rabbit
Clonality Polyclonal

Anti-ADA / Adenosine Deaminase Antibody (clone 608CT2.1.3, AP) - LS-C250089 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 608CT2.1.3

Anti-ADA / Adenosine Deaminase Antibody (clone 608CT2.1.3, Biotin) - LS-C250091 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 608CT2.1.3

Anti-ADA / Adenosine Deaminase Antibody (clone 608CT2.1.3, APC) - LS-C250090 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 608CT2.1.3
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