ADA

Gene Symbol ADA
Entrez Gene 100
Alt Symbol -
Species Human
Gene Type protein-coding
Description adenosine deaminase
Other Description adenosine aminohydrolase
Swissprots Q6LA59 P00813 Q53F92
Accessions AAA78791 CAA26130 CBX85542 CBX85614 EAW75904 EAW75905 EAW75906 EAW75907 P00813 AK123988 AK223397 BAD97117 AL832305 BC007678 AAH07678 BC040226 AAH40226 BI601734 DQ892681 ABM83607 DQ895924 ABM86850 KJ534760 AHW56400 S66773 AAB28742 X02994 CAA26734 XM_005260236 XP_005260293 XM_011528478 XP_011526780 XM_011528479 XP_011526781 XR_244129 NM_000022 NP_000013
Function Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte- epithelial cell adhesion. {ECO:0000269|PubMed:11772392}.
Subcellular Location Cell membrane; Peripheral membrane protein; Extracellular side. Cell junction. Cytoplasmic vesicle lumen {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Colocalized with DPP4 at the cell junction in lymphocyte-epithelial cell adhesion.
Tissue Specificity Found in all tissues, occurs in large amounts in T-lymphocytes and, at the time of weaning, in gastrointestinal tissues.
Top Pathways Primary immunodeficiency, Purine metabolism

adenosine deaminase CRISPR/Cas9 KO Plasmid (h) - sc-402201 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

adenosine deaminase HDR Plasmid (h) - sc-402201-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

adenosine deaminase Double Nickase Plasmid (h) - sc-402201-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

adenosine deaminase Double Nickase Plasmid (h2) - sc-402201-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

adenosine deaminase CRISPR Activation Plasmid (h) - sc-402201-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

adenosine deaminase CRISPR Activation Plasmid (h2) - sc-402201-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

adenosine deaminase Lentiviral Activation Particles (h) - sc-402201-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

adenosine deaminase Lentiviral Activation Particles (h2) - sc-402201-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

adenosine deaminase siRNA (h) - sc-29644 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

adenosine deaminase shRNA Plasmid (h) - sc-29644-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

adenosine deaminase shRNA (h) Lentiviral Particles - sc-29644-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Adenosine Deaminase/ADA RNAi - H00000100-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU048801 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2800 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2800 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02419 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02419

ADA siRNA (Human) - CRH0064 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ADA - MBS8219197 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ADA (NM_000022.2) - SHH231334 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ADA(NM_000022.2) - SHG037819 from Creative biogene

Category siRNA
Species Reactivities Human

Human ADA siRNA - orb260566 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ADA shRNA Plasmid (Human) - CHH0064 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ADA miRNA 3'UTR clone - MiUTR1H-00153 from Creative biogene

Species Reactivities Human
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