| Gene Symbol |
SYTL1
|
| Entrez Gene |
84958
|
| Alt Symbol |
JFC1, SLP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
synaptotagmin-like 1
|
| Other Description |
NADPH oxidase-related, C2 domain-containing protein|exophilin-7|synaptotagmin-like protein 1
|
| Swissprots |
Q5SSC9 Q8IYJ3 Q96BB6 Q96GU6 Q96SI0 Q96S89
|
| Accessions |
EAX07759 EAX07760 EAX07761 EAX07762 Q8IYJ3 AK027902 BAB55444 AK074154 BAB84980 AK096437 AK097172 BAC04970 AK126120 AK293038 BAF85727 AY037157 AAK67636 BC009224 AAH09224 BC015764 AAH15764 BC035725 AAH35725 CB851688 DA435960 DA948740 DQ891217 ABM82143 DQ894400 ABM85326 XM_005246022 XP_005246079 XM_006710990 XP_006711053 XM_006710991 XP_006711054 XM_011542316 XP_011540618 XM_011542317 XP_011540619 XR_946784 NM_001193308 NP_001180237 NM_032872 NP_116261
|
| Function |
May play a role in vesicle trafficking (By similarity). Binds phosphatidylinositol 3,4,5-trisphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:11278853, ECO:0000269|PubMed:18266782}; Peripheral membrane protein {ECO:0000269|PubMed:11278853, ECO:0000269|PubMed:18266782}; Cytoplasmic side {ECO:0000269|PubMed:11278853, ECO:0000269|PubMed:18266782}. Note=Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes.
|
| Tissue Specificity |
Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea. Expressed in cytotoxic T-lymphocytes (CTL). {ECO:0000269|PubMed:11278853, ECO:0000269|PubMed:18266782}.
|