Gene Symbol | SYTL1 |
---|---|
Entrez Gene | 84958 |
Alt Symbol | JFC1, SLP1 |
Species | Human |
Gene Type | protein-coding |
Description | synaptotagmin-like 1 |
Other Description | NADPH oxidase-related, C2 domain-containing protein|exophilin-7|synaptotagmin-like protein 1 |
Swissprots | Q5SSC9 Q8IYJ3 Q96BB6 Q96GU6 Q96SI0 Q96S89 |
Accessions | EAX07759 EAX07760 EAX07761 EAX07762 Q8IYJ3 AK027902 BAB55444 AK074154 BAB84980 AK096437 AK097172 BAC04970 AK126120 AK293038 BAF85727 AY037157 AAK67636 BC009224 AAH09224 BC015764 AAH15764 BC035725 AAH35725 CB851688 DA435960 DA948740 DQ891217 ABM82143 DQ894400 ABM85326 XM_005246022 XP_005246079 XM_006710990 XP_006711053 XM_006710991 XP_006711054 XM_011542316 XP_011540618 XM_011542317 XP_011540619 XR_946784 NM_001193308 NP_001180237 NM_032872 NP_116261 |
Function | May play a role in vesicle trafficking (By similarity). Binds phosphatidylinositol 3,4,5-trisphosphate. Acts as a RAB27A effector protein and may play a role in cytotoxic granule exocytosis in lymphocytes (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:11278853, ECO:0000269|PubMed:18266782}; Peripheral membrane protein {ECO:0000269|PubMed:11278853, ECO:0000269|PubMed:18266782}; Cytoplasmic side {ECO:0000269|PubMed:11278853, ECO:0000269|PubMed:18266782}. Note=Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes. |
Tissue Specificity | Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea. Expressed in cytotoxic T-lymphocytes (CTL). {ECO:0000269|PubMed:11278853, ECO:0000269|PubMed:18266782}. |
JFC1 CRISPR/Cas9 KO Plasmid (h) - sc-413746 from Santa Cruz Biotechnology
|
||||||||
JFC1 HDR Plasmid (h) - sc-413746-HDR from Santa Cruz Biotechnology
|
||||||||
JFC1 Double Nickase Plasmid (h) - sc-413746-NIC from Santa Cruz Biotechnology
|
||||||||
JFC1 Double Nickase Plasmid (h2) - sc-413746-NIC-2 from Santa Cruz Biotechnology
|
||||||||
JFC1 CRISPR Activation Plasmid (h) - sc-413746-ACT from Santa Cruz Biotechnology
|
||||||||
JFC1 CRISPR Activation Plasmid (h2) - sc-413746-ACT-2 from Santa Cruz Biotechnology
|
||||||||
JFC1 Lentiviral Activation Particles (h) - sc-413746-LAC from Santa Cruz Biotechnology
|
||||||||
JFC1 Lentiviral Activation Particles (h2) - sc-413746-LAC-2 from Santa Cruz Biotechnology
|
||||||||
JFC1 siRNA (h) - sc-40717 from Santa Cruz Biotechnology
|
||||||||
JFC1 shRNA Plasmid (h) - sc-40717-SH from Santa Cruz Biotechnology
|
||||||||
JFC1 shRNA (h) Lentiviral Particles - sc-40717-V from Santa Cruz Biotechnology
|
||||||||
SYTL1 RNAi - H00084958-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU055441 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN20930 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20930 from Sigma-Aldrich
|
||||||||
SYTL1 siRNA (Human) - CRJ3726 from Cohesion Biosciences
|
||||||||
SYTL1 - MBS8230176 from MyBioSource
|
||||||||
shRNA set against Human SYTL1 (NM_032872.2) - SHH422116 from Creative biogene
|
||||||||
Human SYTL1 siRNA - orb274227 from Biorbyt
|
||||||||
SYTL1 shRNA Plasmid (Human) - CHJ3726 from Cohesion Biosciences
|
||||||||
SYTL1 miRNA 3'UTR clone - MiUTR3H-09687 from Creative biogene
|