Gene Symbol |
B3GNT4
|
Entrez Gene |
79369
|
Alt Symbol |
B3GN-T4, beta3Gn-T4
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
|
Other Description |
BGnT-4|N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4|beta-1,3-Gn-T4|beta-1,3-N-acetylglucosaminyltransferase 4|beta-1,3-N-acetylglucosaminyltransferase bGn-T4
|
Swissprots |
Q8WWR5 Q9C0J1 Q8ND21 Q8N5W4 Q8WY02 Q96QH5 Q8N934
|
Accessions |
AAL37219 EAW98308 EAW98309 Q9C0J1 AB049586 BAB21532 AJ130848 CAC45045 AJ278962 CAC82375 AK095746 BAC04622 AL834452 CAD39112 AY358940 AAQ89299 BC030247 BC031399 AAH31399 DQ891284 ABM82210 DQ894469 ABM85395 XM_011538732 XP_011537034 NM_030765 NP_110392
|
Function |
Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Has activity for type 2 oligosaccharides. {ECO:0000269|PubMed:11042166}.
|
Subcellular Location |
Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
Tissue Specificity |
Mainly expressed in brain tissues such as whole brain, hippocampus, amygdala, cerebellum and caudate nucleus. Also expressed in colon, esophagus and kidney. {ECO:0000269|PubMed:11042166}.
|
Top Pathways |
Glycosphingolipid biosynthesis - lacto and neolacto series
|