Gene Symbol | B3GNT4 |
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Entrez Gene | 79369 |
Alt Symbol | B3GN-T4, beta3Gn-T4 |
Species | Human |
Gene Type | protein-coding |
Description | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
Other Description | BGnT-4|N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4|beta-1,3-Gn-T4|beta-1,3-N-acetylglucosaminyltransferase 4|beta-1,3-N-acetylglucosaminyltransferase bGn-T4 |
Swissprots | Q8WWR5 Q9C0J1 Q8ND21 Q8N5W4 Q8WY02 Q96QH5 Q8N934 |
Accessions | AAL37219 EAW98308 EAW98309 Q9C0J1 AB049586 BAB21532 AJ130848 CAC45045 AJ278962 CAC82375 AK095746 BAC04622 AL834452 CAD39112 AY358940 AAQ89299 BC030247 BC031399 AAH31399 DQ891284 ABM82210 DQ894469 ABM85395 XM_011538732 XP_011537034 NM_030765 NP_110392 |
Function | Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Has activity for type 2 oligosaccharides. {ECO:0000269|PubMed:11042166}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Tissue Specificity | Mainly expressed in brain tissues such as whole brain, hippocampus, amygdala, cerebellum and caudate nucleus. Also expressed in colon, esophagus and kidney. {ECO:0000269|PubMed:11042166}. |
Top Pathways | Glycosphingolipid biosynthesis - lacto and neolacto series |
β3Gn-T4 siRNA (h) - sc-95932 from Santa Cruz Biotechnology
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β3Gn-T4 shRNA Plasmid (h) - sc-95932-SH from Santa Cruz Biotechnology
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β3Gn-T4 shRNA (h) Lentiviral Particles - sc-95932-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU085251 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3808 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3808 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00258 from Sigma-Aldrich
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B3GNT4 siRNA (Human) - CRJ2376 from Cohesion Biosciences
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B3GNT4 - MBS8224217 from MyBioSource
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shRNA set against Human B3GNT4 (NM_030765.2) - SHH244262 from Creative biogene
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shRNA set against Human B3GNT4(NM_030765.2) - SHG088953 from Creative biogene
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B3GNT4 shRNA Plasmid (Human) - CHJ2376 from Cohesion Biosciences
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B3GNT4 miRNA 3'UTR clone - MiUTR1H-00771 from Creative biogene
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