SMG8

Gene Symbol SMG8
Entrez Gene 55181
Alt Symbol C17orf71
Species Human
Gene Type protein-coding
Description SMG8 nonsense mediated mRNA decay factor
Other Description amplified in breast cancer gene 2 protein|protein SMG8|protein smg-8 homolog|smg-8 homolog, nonsense mediated mRNA decay factor
Swissprots Q8TDN0 Q8ND04 Q9H5P5 Q8N5U5 Q9NVQ1
Accessions EAW94413 EAW94414 EAW94415 Q8ND04 AF349467 AAL83913 AK001449 BAA91699 AK026858 BAB15576 AL834490 CAD39148 BC020957 AAH20957 BC031604 AAH31604 JF432378 ADZ15595 NM_018149 NP_060619
Function Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity. {ECO:0000269|PubMed:19417104}.

SMG8 CRISPR/Cas9 KO Plasmid (h) - sc-408902 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMG8 HDR Plasmid (h) - sc-408902-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMG8 Double Nickase Plasmid (h) - sc-408902-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMG8 Double Nickase Plasmid (h2) - sc-408902-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMG8 CRISPR Activation Plasmid (h) - sc-408902-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMG8 CRISPR Activation Plasmid (h2) - sc-408902-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMG8 Lentiviral Activation Particles (h) - sc-408902-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMG8 Lentiviral Activation Particles (h2) - sc-408902-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMG8 siRNA (h) - sc-93833 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SMG8 shRNA Plasmid (h) - sc-93833-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SMG8 shRNA (h) Lentiviral Particles - sc-93833-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU082011 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4478 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4478 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01716 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01716

SMG8 siRNA (Human) - CRJ0534 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SMG8 - MBS8236282 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SMG8 (NM_018149.6) - SHH413448 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human C17orf71(NM_018149.6) - SHG117109 from Creative biogene

Category siRNA
Species Reactivities Human

SMG8 shRNA Plasmid (Human) - CHJ0534 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SMG8 miRNA 3'UTR clone - MiUTR1H-01172 from Creative biogene

Species Reactivities Human
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