Gene Symbol | AGPAT6 |
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Entrez Gene | 137964 |
Alt Symbol | 1-AGPAT 6, LPAAT-zeta, LPAATZ, TSARG7 |
Species | Human |
Gene Type | protein-coding |
Description | 1-acylglycerol-3-phosphate O-acyltransferase 6 |
Other Description | 1-AGP acyltransferase 6|1-acyl-sn-glycerol-3-phosphate acyltransferase zeta|1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)|glycerol-3-phosphate acyltransferase 6|lysophosphatidic acid acyltransferase zeta|testis spermatogenesis apoptosis-related protein 7 |
Swissprots | Q86UL3 Q86V89 |
Accessions | CAT16184 EAW63253 EAW63254 EAW63255 Q86UL3 AF317516 AAG33063 AF406612 AAP21893 AL834255 CAD38930 AY358670 AAQ89033 AY513610 AAS82774 BC051377 AAH51377 BC061884 AAH61884 BU620295 DB470455 XM_011544392 XP_011542694 XM_011544393 XP_011542695 XM_011544394 XP_011542696 XM_011544395 XP_011542697 XM_011544396 XP_011542698 XM_011544397 XP_011542699 NM_178819 NP_848934 |
Function | Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Active against both saturated and unsaturated long- chain fatty acyl-CoAs. {ECO:0000269|PubMed:18238778}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:18238778}; Multi-pass membrane protein {ECO:0000269|PubMed:18238778}. |
Tissue Specificity | Ubiquitous. Relatively high level of expression in skeletal muscle, heart and testis. Relatively low level of expression in lung. {ECO:0000269|PubMed:12938015, ECO:0000269|PubMed:18238778}. |
Top Pathways | Glycerolipid metabolism, Glycerophospholipid metabolism |
Human GPAT4 full length protein - ab165410 from Abcam
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Human GPAT4 peptide - ab91636 from Abcam
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Human GPAT4 protein fragment - ab165411 from Abcam
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AGPAT6 Antibody Blocking Peptide - LS-E22251 from LifeSpan Bioscience
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AGPAT6 Antibody Blocking Peptide - LS-E10243 from LifeSpan Bioscience
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AGPAT6 Blocking Peptide - NB100-2389PEP from Novus Biologicals
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AGPAT6 Peptide - NB100-2390PEP from Novus Biologicals
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Recombinant Human AGPAT6 Protein - H00137964-P01 from Novus Biologicals
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Recombinant Human AGPAT6 Protein - H00137964-Q01 from Novus Biologicals
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AGPAT6-Antibody-N-term-Blocking-Peptide - BP9647a from Abgent, a WuXi AppTec company
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AGPAT6 Blocking Peptide - 33R-6449 from Fitzgerald
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AGPAT6 - H00137964-P01 from Acris Antibodies
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AGPAT6 - H00137964-Q01-10 from Acris Antibodies
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AGPAT6 - H00137964-Q01-25 from Acris Antibodies
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AGPAT6 fusion protein - Ag10294 from Proteintech Group
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AGPAT6 fusion protein - Ag10302 from Proteintech Group
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Recombinant Human AGPAT6, GST-tagged - AGPAT6-9478H from Creative Biomart
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AGPAT6 Protein - abx164996 from Abbexa
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AGPAT6 Recombinant Protein Antigen - NBP1-85061PEP from Novus Biologicals
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AGPAT6 Peptide, Human - M34GP00381H from Creative Peptides
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AGPAT6 fusion protein - Ag26732 from Proteintech Group
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Glycerol-3-phosphate acyltransferase 4 (AGPAT6), Recombinant Protein - MBS7007404 from MyBioSource
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