| Gene Symbol | NSF |
|---|---|
| Entrez Gene | 4905 |
| Alt Symbol | SKD2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | N-ethylmaleimide-sensitive factor |
| Other Description | N-ethylmaleimide-sensitive factor-like protein|N-ethylmaleimide-sensitive fusion protein|NEM-sensitive fusion protein|vesicle-fusing ATPase|vesicular-fusion protein NSF |
| Swissprots | B4DFA2 Q9UKZ2 Q8N6D7 A8K2D9 P46459 |
| Accessions | CAH56804 EAW57706 EAW57707 P46459 AF102846 AAF04745 AF135168 AAF70545 AK226078 AK290204 BAF82893 AK294001 BAG57363 AK294727 BAG57874 AK294886 BAG57980 AK299031 BAH12933 AK299786 BAG61667 AK316057 BAH14428 AL049276 BC013314 AAH13314 BC030613 AAH30613 BM451383 DB460965 U03985 AAA17411 U80997 AAG23890 XM_011524863 XP_011523165 XM_011546358 XP_011544660 XM_011547488 XP_011545790 NM_006178 NP_006169 NR_040116 |
| Function | Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm. |
| Top Pathways | Vasopressin-regulated water reabsorption, Synaptic vesicle cycle, GABAergic synapse |