Gene Symbol | PLXNC1 |
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Entrez Gene | 10154 |
Alt Symbol | CD232, PLXN-C1, VESPR |
Species | Human |
Gene Type | protein-coding |
Description | plexin C1 |
Other Description | plexin (semaphorin receptor)|plexin-C1|receptor for viral semaphorin protein|receptor for virally-encoded semaphorin|virus-encoded semaphorin protein receptor |
Swissprots | Q59H25 O60486 |
Accessions | EAW97500 O60486 AA609130 AB208934 BAD92171 AF030339 AAC18823 AF035307 AK295226 BAG58219 AK304327 BAH14160 AK307920 AK308985 BC029934 BC148590 AAI48591 BC156867 AAI56868 XM_006719186 XP_006719249 XM_011537730 XP_011536032 XM_011537731 XP_011536033 XR_944471 NM_005761 NP_005752 NR_037687 |
Function | Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8 (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Detected in heart, brain, lung, spleen and placenta. {ECO:0000269|PubMed:9586637}. |
Top Pathways | Axon guidance |
Human PLXNC1 protein fragment - ab160845 from Abcam
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PLXNC1 / Plexin C1 Antibody Blocking Peptide - LS-E2538 from LifeSpan Bioscience
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Recombinant Human Plexin C1 Protein - H00010154-Q01 from Novus Biologicals
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PLXNC1-Antibody-C-term-Blocking-peptide - BP13576b from Abgent, a WuXi AppTec company
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Recombinant Human Plexin C1, CF - 3887-PC-050 from R&D Systems
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CD232 / PLXNC1 - H00010154-Q01-10 from Acris Antibodies
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CD232 / PLXNC1 - H00010154-Q01-25 from Acris Antibodies
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PLXNC1 fusion protein - ag18225 from Proteintech Group
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PLXNC1 fusion protein - Ag18170 from Proteintech Group
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Recombinant Human PLXNC1, His-tagged - PLXNC1-1001H from Creative Biomart
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Recombinant Human Plexin-C1(PLXNC1) ,partial - CSB-YP018225HU CSB-EP018225HU CSB-BP018225HU CSB-MP018225HU from Cusabio
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Recombinant Human Plexin C1 Protein, CF - 3887-PC from R&D Systems
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CD232 / PLXNC1 - TP311396 from Acris Antibodies
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Plexin C1, Recombinant Protein - MBS635720 from MyBioSource
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Plexin-C1 (PLXNC1), partial, Recombinant Protein - MBS1237757 from MyBioSource
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CD232 Blocking Peptide - abx061926 from Abbexa
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PLXNC1 Peptide, Human - M34GP11993H from Creative Peptides
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CD232 Blocking Peptide - CBP7316 from Cohesion Biosciences
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Plexin C1 Recombinant Protein Antigen - NBP2-57282PEP from Novus Biologicals
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Recombinant Human Plexin C1 Protein, CF - 3887-PC from Novus Biologicals
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Recombinant Mouse Plexin C1 Protein, CF - 5375-PC from Novus Biologicals
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