Gene Symbol | EEF1E1 |
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Entrez Gene | 9521 |
Alt Symbol | AIMP3, P18 |
Species | Human |
Gene Type | protein-coding |
Description | eukaryotic translation elongation factor 1 epsilon 1 |
Other Description | ARS-interacting multifunctional protein 3|aminoacyl tRNA synthetase complex-interacting multifunctional protein 3|eukaryotic translation elongation factor 1 epsilon-1|multisynthase complex auxiliary component p18|p18 component of aminoacyl-tRNA synthetase complex |
Swissprots | O43324 Q5THS2 C9JLK5 |
Accessions | EAW55227 EAW55231 O43324 AB011079 BAA24926 AF054186 AAC39916 AI374688 AI394376 AV714140 BC005291 AAH05291 BG183264 BP235196 BT007306 AAP35970 CK002875 DQ893502 ABM84428 EU176776 ABW03577 NM_001135650 NP_001129122 NM_004280 NP_004271 |
Function | Positive modulator of ATM response to DNA damage. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15680327}. Nucleus {ECO:0000269|PubMed:15680327}. Note=Cytoplasmic under growth arrest conditions. Translocated into the nucleus when growth resumes (S phase) and following DNA damage. |
Tissue Specificity | Down-regulated in various cancer tissues. {ECO:0000269|PubMed:15680327}. |
EF-1 ε1 siRNA (h) - sc-77233 from Santa Cruz Biotechnology
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EF-1 ε1 shRNA Plasmid (h) - sc-77233-SH from Santa Cruz Biotechnology
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EF-1 ε1 shRNA (h) Lentiviral Particles - sc-77233-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU036321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7668 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7668 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04371 from Sigma-Aldrich
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EEF1E1 siRNA (Human) - CRH6327 from Cohesion Biosciences
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EEF1E1 - MBS8228431 from MyBioSource
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shRNA set against Human EEF1E1 (NM_004280.4) - SHH283313 from Creative biogene
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Human EEF1E1 siRNA - orb266829 from Biorbyt
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EEF1E1 shRNA Plasmid (Human) - CHH6327 from Cohesion Biosciences
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EEF1E1 miRNA 3'UTR clone - MiUTR3H-10476 from Creative biogene
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EEF1E1 miRNA 3'UTR clone - MiUTR3H-10477 from Creative biogene
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