Gene Symbol |
CLIC3
|
Entrez Gene |
9022
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
chloride intracellular channel 3
|
Other Description |
chloride intracellular channel protein 3
|
Swissprots |
Q5SPZ7 O95833
|
Accessions |
EAW88329 EAW88330 O95833 AF102166 AAD16450 AI741256 BC007012 AAH07012 BF439361 BM043659 CR542066 CAG46863 HQ447985 ADQ32467 NM_004669 NP_004660
|
Function |
Can insert into membranes and form chloride ion channels. May participate in cellular growth control. {ECO:0000269|PubMed:9880541}.
|
Subcellular Location |
Nucleus. Membrane; Single-pass membrane protein. Cytoplasm. Note=Predominantly nuclear. Some protein was found in the cytoplasm. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity). {ECO:0000250}.
|
Tissue Specificity |
Detected in placenta (at protein level). Widely expressed. High expression is found in placenta followed by lung and heart. Low expression in skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:17027078, ECO:0000269|PubMed:9880541}.
|