Gene Symbol | CLIC3 |
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Entrez Gene | 9022 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | chloride intracellular channel 3 |
Other Description | chloride intracellular channel protein 3 |
Swissprots | Q5SPZ7 O95833 |
Accessions | EAW88329 EAW88330 O95833 AF102166 AAD16450 AI741256 BC007012 AAH07012 BF439361 BM043659 CR542066 CAG46863 HQ447985 ADQ32467 NM_004669 NP_004660 |
Function | Can insert into membranes and form chloride ion channels. May participate in cellular growth control. {ECO:0000269|PubMed:9880541}. |
Subcellular Location | Nucleus. Membrane; Single-pass membrane protein. Cytoplasm. Note=Predominantly nuclear. Some protein was found in the cytoplasm. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity). {ECO:0000250}. |
Tissue Specificity | Detected in placenta (at protein level). Widely expressed. High expression is found in placenta followed by lung and heart. Low expression in skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:17027078, ECO:0000269|PubMed:9880541}. |
CLIC3 CRISPR/Cas9 KO Plasmid (h) - sc-407932 from Santa Cruz Biotechnology
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CLIC3 HDR Plasmid (h) - sc-407932-HDR from Santa Cruz Biotechnology
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CLIC3 Double Nickase Plasmid (h) - sc-407932-NIC from Santa Cruz Biotechnology
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CLIC3 Double Nickase Plasmid (h2) - sc-407932-NIC-2 from Santa Cruz Biotechnology
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CLIC3 CRISPR Activation Plasmid (h) - sc-407932-ACT from Santa Cruz Biotechnology
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CLIC3 CRISPR Activation Plasmid (h2) - sc-407932-ACT-2 from Santa Cruz Biotechnology
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CLIC3 Lentiviral Activation Particles (h) - sc-407932-LAC from Santa Cruz Biotechnology
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CLIC3 Lentiviral Activation Particles (h2) - sc-407932-LAC-2 from Santa Cruz Biotechnology
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CLIC3 siRNA (h) - sc-62126 from Santa Cruz Biotechnology
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CLIC3 shRNA Plasmid (h) - sc-62126-SH from Santa Cruz Biotechnology
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CLIC3 shRNA (h) Lentiviral Particles - sc-62126-V from Santa Cruz Biotechnology
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CLIC3 RNAi - H00009022-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN6230 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6230 from Sigma-Aldrich
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CLIC3 siRNA (Human) - CRH5949 from Cohesion Biosciences
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CLIC3 - MBS827269 from MyBioSource
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shRNA set against Human CLIC3 (NM_004669.2) - SHH265297 from Creative biogene
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shRNA set against Human CLIC3(NM_004669.2) - SHG182767 from Creative biogene
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Human CLIC3 siRNA - orb266451 from Biorbyt
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CLIC3 shRNA Plasmid (Human) - CHH5949 from Cohesion Biosciences
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CLIC3 miRNA 3'UTR clone - MiUTR1H-02222 from Creative biogene
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